New

Senior Director Clinical Biomarkers, BioPharma Business Development

San Francisco, CA; US Remote

The Senior Director Clinical Biomarkers, BioPharma Business Development will provide strategic,

scientific, and organizational leadership across a broad oncology diagnostics portfolio. This

executive will be responsible for defining and advancing biomarker and translational medicine

strategies across early- and late-stage BioPharma collaborations in support of Natera’s strategic

goals eg TOMR and surrogacy in collaboration with Natera’s lifecycle and clinical development

teams.

 

The ideal candidate will bring deep expertise in oncology drug development, biomarker

strategy, and translational research, with experience spanning Phase 1–3 studies and multiple

therapeutic modalities, including immunotherapy, targeted therapy, and antibody-drug

conjugates.

 

Key Responsibilities

 Lead translational medicine and clinical biomarker strategy across oncology programs

within and beyond the BioPharma BD portfolio.

 Define and oversee biomarker plans supporting late-stage development in solid tumors

within the BioPharma space (Pharma Lab Services, BD partnerships) including assay

strategy, translational endpoints, data generation, data interpretation, publication

planning, and regulatory filing support.

 Partner closely with clinical development, bioinformatics, medical affairs, regulatory,

diagnostics, and commercial teams to ensure assay development portfolio and

biomarker strategies are aligned with overall BioPharma BD needs.

 Work with external partners on their Natera-supported translational research efforts to

help them leverage Natera capabilities to optimize the value of their projects: these may

include identifying novel targets, characterizing resistance mechanisms, developing

novel predictive biomarkers and next-generation clinical tools, including blood-based

biomarkers, digital pathology, radiomics, and AI/ML-enabled approaches.

 Support development and lifecycle strategies that enable successful product

differentiation, launch readiness, reimbursement, and broader clinical adoption.

 

BioPharma Deliverables

 Contribute to study design and evidence-generation plans that support our BioPharma

efforts across BD, Pharma Lab Services, and internal R&D.

 Work with the RWD, AI, and bioinformatics teams to develop use cases for existing data

and build out new concepts for new data types as they are created.

 Apply translational insights to inform patient selection, development decisions, and

clinical differentiation strategies for our customers.

 

External Relationships & Strategic Engagement

 Establish and lead strategic collaborations with BioPharma partners, academic

institutions, cooperative groups, scientific consortia, and key opinion leaders.

 Represent the company in external scientific and clinical initiatives that shape the future

of biomarker-enabled oncology development.

 Build productive external partnerships that accelerate innovation, evidence generation,

and adoption of novel translational approaches.

 

External Scientific Presence

 Serve as a visible scientific leader through publications, invited presentations, advisory

participation, and broader thought leadership in oncology and precision medicine.

 Maintain strong credibility in the external scientific community, with the ability to

engage effectively with academic leaders, consortia, and industry partners.

 Contribute to the company’s scientific reputation through high-impact external

presence and publication strategy.

 

Preferred Qualifications

 Advanced degree in a relevant scientific discipline; PhD, MD, DVM, or equivalent

strongly preferred.

 15+ years of relevant experience in translational medicine, clinical biomarker

development, oncology drug development, or related fields.

 Significant experience in biomarker-driven clinical development and medical affairs

across early- and late-stage oncology programs.

 Demonstrated success in building external scientific relationships and representing

organizations in high-profile external settings.

 Strong record of scientific leadership, cross-functional collaboration, and strategic

execution.

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$248,100 - $310,100 USD

Compensation & Total Rewards 

This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of  hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.

This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:

  • Annual performance incentive bonus

  • Long-term equity awards

  • Comprehensive health benefits (medical, dental, vision)

  • 401(k) with company match

  • Generous paid time off and company holidays

  • Additional wellness and work-life benefits

Compensation Range

$248,100 - $310,100 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents. 

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
- BBB announcement on job scams 
- FBI Cyber Crime resource page 

Create a Job Alert

Interested in building your career at Natera? Get future opportunities sent straight to your email.

Apply for this job

*

indicates a required field

Resume/CV*

Accepted file types: pdf, doc, docx, txt, rtf

Cover Letter

Accepted file types: pdf, doc, docx, txt, rtf

Employment

Select...
Select...

Education

Select...
Select...
Select...
Select...
Select...
Select...
Select...

Natera values transparency and fair hiring practices. Disclosure of a family relationship does not automatically disqualify you from employment. This information helps us comply with our internal policies on conflicts of interest and reporting structures.

Select...
Select...
Select...
Select...

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Natera’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Select...
Select...
Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Select...

Voluntary Self-Identification of Disability

Form CC-305
Page 1 of 1
OMB Control Number 1250-0005
Expires 04/30/2026

Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
  • Traumatic brain injury
Select...

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.