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Bioinformatics Manager (Oncology Product Development)

San Carlos, CA

Natera is currently seeking a Bioinformatics Manager to join the Bioinformatics team focused on Oncology Product Development. In this role, the individual will manage a team of Bioinformaticians and Data Scientists and provide technical leadership in the design, development and validation of ctDNA-based diagnostic tests. This position requires extensive cross-functional collaboration with biostatistics, molecular biology, software engineering and commercial departments. The ideal candidate will have a strong background in bioinformatics and data science, optimally with experience in the analysis or modeling of DNA methylation data, and an established record of project and technical leadership.

PRIMARY RESPONSIBILITIES:

  • Lead the effort to develop, optimize, and improve tools and analysis pipelines for diagnostic tests, including the detection of cancer-associated variants or methylation patterns and the implementation of evidence-based quality control thresholds.
  • Provide technical leadership for product development projects by representing the team in cross-functional interactions and moving products through the full development process, from research through commercial launch.
  • Supervise bioinformatics scientists and data scientists, managing their technical contributions, prioritizing resources, and taking responsibility for their technical and professional development.
  • Provide input on experiment design, analysis and interpretation based on expert understanding of Natera’s technology and relevant mathematical principles.
  • Work at a high level of independence and responsibilities in carrying out assignments.
  • Contribute to our intellectual property portfolio.
  • Set standards for rigorous data analysis and lead the production of high-quality documentation. 

QUALIFICATIONS:

  • Master’s degree or Ph.D. in a quantitative discipline (bioinformatics, engineering, applied mathematics, statistics, or similar).
  • Minimum of 4-8 years of post-graduate experience in a data science and/or bioinformatics role and 1-3 years of experience as technical lead in diagnostics or a related field
  • Experience moving algorithm-based products through commercialization and launch in a medical or biological application such as diagnostic testing, medical imaging, or biotechnology

Desirable, but not required:

  • Prior experience analyzing or modeling DNA methylation data.

KNOWLEDGE, SKILLS, AND ABILITIES:

  • Experience using Python or R for scientific data analysis and visualization.
  • Strong foundation in statistical modeling/machine learning, including probability theory and estimation/classification methods.
  • Experience with analysis of next-generation sequencing data, preferably including algorithm development or optimization.
  • Proven ability to apply mathematical principles to solve real estimation problems and implement practical solutions.
  • Excellent analytical, problem-solving and decision-making skills to independently make sound judgments and find creative solutions to moderately complex problems.
  • Experience leading technical projects, including defining and meeting project milestones, delegating tasks to more junior team members, and ensuring the quality of technical deliverables.
  • Excellent communication skills and the desire to work in a dynamic and collaborative environment.

Compensation & Total Rewards 

This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of  hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.

This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:

  • Annual performance incentive bonus

  • Long-term equity awards

  • Comprehensive health benefits (medical, dental, vision)

  • 401(k) with company match

  • Generous paid time off and company holidays

  • Additional wellness and work-life benefits

Compensation Range

$154,000 - $192,500 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents. 

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
- BBB announcement on job scams 
- FBI Cyber Crime resource page 

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