Company info

NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale.

Description

NewLimit is seeking a Senior/Research Associate with experience in molecular biology to join our Single Cell Technology group. Single cell genomics is one of the key enabling technologies for our research programs, allowing us to measure the transcriptional and epigenetic state of millions of cells to guide therapeutic discovery.

As a member of our team, you will:

• Collaborate with our Epigenetic Editing team to perform large-scale, single cell perturbation experiments with custom chemistries
• Perform state-of-the-art single cell profiling experiments to map epigenetic features of age-related disease and evaluate interventions
• Measure the safety & efficacy of reprogramming medicines with frontier genomics methods
• Isolate, culture, and prepare cells for single cell profiling experiments

Requirements

• Bachelor’s degree in cell biology, molecular biology, or a related natural science or industry experience
• 2+ years of work experience in a cell or molecular biology laboratory (academic or industry)
• Experience with standard molecular biology workflows (e.g., nucleic acid extraction, PCR, NGS library construction, library quantification and QC)
• Experience with cell and sample handling (e.g., mammalian cell culture, primary tissue dissociation, nuclei isolation, cryopreservation)

Nice to have

• Experience operating a next generation sequencing instrument.
• Experience with single cell genomics methods (such as 10x Genomics, PIP-seq, Scale Bio, Parse Bio, Mission Bio, Drop-seq, Perturb-seq/CROProp-seq or similar)
• Experience troubleshooting or optimizing NGS workflows.
• Experience with flow cytometry sorting for single-cell preparations.
• Experience programming and/or using automated liquid handling platforms.
• Basic computational skills for next-generation sequencing analysis (Python programming, Unix, Seurat/Scanpy).

Benefits

• Health, dental, and vision insurance
• 401(k) with company match
• Industry-leading paid time off (PTO) -- 20 days/year for all employees + holidays
• Paid parental leave
• Meals and snacks on-site

Salary Range: $55,000 to $98,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. NewLimit offers a competitive benefits package, which includes a 401k, healthcare coverage, and 20 days of PTO. Learn more at: https://www.newlimit.com/careers   *This compensation and benefits information is based on Company's good faith estimate as of the date of publication and may be modified in the future.