AI Scientist

WHY NOETIK

NOETIK is a frontier therapeutics company harnessing AI to deeply understand human biology and redefine clinical outcomes in oncology. Leveraging the largest proprietary multimodal oncology dataset of its kind, uniquely integrating deep spatial profiling with routine clinical assays, NOETIK’s foundation AI models precisely match therapeutic targets to patient subpopulations and accurately predict clinical efficacy. This AI-first approach elevates therapeutic development from probabilistic guesswork to precision science.

THE OPPORTUNITY

We’re looking for an AI scientist to lead the development, training, and evaluation of custom world models of patient cancer biology. The models will be built using NOETIK’s extensive pan-cancer multimodal spatial dataset – the largest of its kind – combined with other datasets and modalities, and will be used for drug development, clinical trial design, and deep biological insight. There is no blueprint for how to build models that make the most of this data; we’re looking for somebody who is excited to explore, experiment, and forge this field with us by developing new architectures, loss functions, and evals. The AI team at Noetik operates as a fast-paced research lab emphasizing creativity and urgency in our work. We believe that the fastest way to make an impact for patients is to pair big ideas with rigorous science. This is fundamental research applied to real problems: the breakthroughs you make in your research will translate directly to improved care for patients.

In this role you will be responsible for the development and evaluation of Noetik's custom models. You will be empowered to pursue a research agenda that is supported by substantial GPU allocation per researcher, work alongside a data-generating lab on “lab in the loop” iterations for model exploration and improvement, and collaborate with a world-class team of engineers and researchers.

WHAT YOU’LL DO:

• Design, implement, and train foundation models that integrate biology across spatial scales and measurement modalities
• Scale model recipes to massive datasets and compute infrastructure
• Contribute ideas in internal lab meetings and journal clubs, learn from the expertise on the team, and share your own
• Identify meaningful benchmark tasks and evaluations for biology foundation models, and systematically evaluate open source alternatives on those benchmarks
• Own research projects from conception to execution, communicate results to the broader team, make findings legible to biologists and partners, and collaborate with domain experts
• Present your research at leading conferences in AI and biology
• Rapidly iterate on research ideas, identify the highest leverage experiments to run, and make informed decisions with conviction

QUALIFICATIONS:

No prior experience in biology or oncology is required. We welcome applicants with backgrounds in computer vision, robotics, NLP, computational biology, neuroscience, and more. If you have experience obsessively checking loss curves, we want to hear from you. Some indicators that you have relevant experience include:

• Publications and presentations in leading journals and machine learning conferences (e.g. NeurIPS, ICLR, ICML, CVPR)
• A PhD in a quantitative field using modern machine learning methods, or equivalent research experience
• Experience writing model architecture code and datasets in PyTorch, training and optimizing models, and evaluating trained models
• Deep knowledge of modern machine learning architectures and self-supervised learning approaches (autoencoders, diffusion, flow-matching, autoregressive decoders)
• Familiarity with training and inference in large-scale distributed systems, including advanced parallelism approaches and supporting frameworks
• Practical use of modern AI tools to accelerate scientific work without sacrificing integrity and rigor

Life@Noetik

Great science is a team sport. We are focused on creating a culture where brilliant people from different backgrounds can solve hard problems together. At Noetik, culture isn't just about perks; it’s about building a vibrant, collaborative community where everyone has the tools and the autonomy to thrive.

How We Work

Location & Collaboration: our primary lab and office space is located in South San Francisco. We operate as a hybrid organization, utilizing Slack, Zoom, and a modern tech stack to stay seamlessly connected regardless of time zone.

Intentional Connection: we believe that high-impact work requires intentional time together. We keep the team aligned through monthly All-Hands meetings and Quarterly Co-working Weeks at our South San Francisco office. Once a year, we gather for an Annual Reset - a week-long offsite dedicated to high-level strategy, collaboration and team bonding. Past locations have included Austin, TX, Park City, UT, and Boulder, CO.

Onsite Community: For team members working onsite, we foster a collaborative environment and refuel with daily catered lunches from great local restaurants and Boba Thursday - a small but meaningful tradition where we step away from our desks to connect over a break.

How We Support You

Health & Wellbeing: we provide generous health, dental, and vision insurance, with premiums fully covered for both employees and their dependents (depending on your plan choice). Our coverage is designed to be comprehensive and accessible, featuring modern care platforms like OneMedical, Midi Health, Spring Health, and XP Health. To further support your needs, we offer HSA and FSA accounts, dependent care savings, an EAP, resources for mental health (Rula), and health care navigation and advocacy (Rightway).

Time Off & Synchronized Breaks: we offer Flexible PTO to manage your personal time, alongside nine paid holidays. We also offer synchronized breaks so that the team can fully unplug simultaneously -  two full-week company breaks (the first week of July and the last week of December), plus the Friday after Thanksgiving.

Compensation & Financial Benefits: our financial package includes a competitive base salary, stock options, and a 401(k) plan with an employer match. We provide a safety net through fully-covered disability, life and AD&D insurance, as well as generous parental leave. We also offer a suite of financial and lifestyle tools, including SoFi, Multiply Mortgage, and optional programs for pet insurance, legal services, and identity theft protection.

We believe that the highest performing teams include people from a wide variety of backgrounds and experiences who respectfully challenge each other.  We are committed to an open, diverse and inclusive culture for all employees. Noetik is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, physical or mental disability, medical condition, marital status, veteran status and any other characteristics protected under applicable federal, state and local laws.