Clinical Scientist (Director Level)

About Peptilogics: Leaders in Scalable, Rational Design

Peptilogics is a clinical-stage biotechnology company that designs and develops novel peptide therapeutics. The company leverages machine learning, automation, and peptide synthesis to build platforms for science at scale. With its foundations in drug development and engineering, the company’s platforms vertically integrate proprietary hardware, software, bioinformatics, chemistry, and molecular biology to advance basic research, target validation, and clinical trials.

Position Overview 

The Clinical Scientist will serve as a scientific and operational leader across Peptilogics’ clinical development efforts. This role provides expert input into study design, execution, and data interpretation, working cross-functionally to ensure scientific rigor, regulatory alignment, and data integrity across clinical trials. The ideal candidate brings strategic insight, scientific depth, and hands-on experience across multiple phases of development.

This individual will work closely with cross-functional stakeholders to lead core clinical programs, ensure study quality, and inform development strategy. Strong communication skills and prior experience presenting to internal and external stakeholders – including investigators, advisors, and regulators – are essential. Expertise in infectious diseases is preferred; prior experience with orthopedic or operative products is a plus. This role requires comfort navigating ambiguity and driving clinical execution in a dynamic, fast-paced biotech environment.

Essential Functions 

• Provide strategic and tactical input into study design, methodology, and protocol development, incorporating standards of care, advisory input, and biostatistical guidance
• Lead the scientific review, analysis, and interpretation of clinical trial data, ensuring data integrity and protocol adherence
• Drive the preparation of clinical content for study reports, investigator brochures, safety reports (e.g., DSURs), and internal/external presentations
• Serve as the clinical counterpart to Clinical Operations, Data Management, Biostatistics, and Programming; contribute to development of statistical analysis plans, case report forms (CRFs), and data review processes
• Communicate key clinical and scientific updates to project teams and senior leadership, identifying risks, delays, or issues as they arise
• Develop and deliver oral and written scientific presentations to investigators, advisory boards, external stakeholders, and internal audiences
• Mentor and manage junior clinical personnel and contribute to the development of clinical team capabilities

Additional Duties and Responsibilities 

• Collaborate with Medical Monitors to support clinical development planning and strategic input across program documents
• Assist in operational aspects of trial conduct, including assay development, training, protocol compliance, and medical data review
• Contribute to the design and execution of investigator meetings, clinical advisory boards, and data monitoring boards, including scientific content preparation
• Support preparation of regulatory submissions and documentation for FDA and other health authorities
• Assist in writing and reviewing scientific publications, abstracts, and conference materials in collaboration with medical writing or research colleagues
• Perform other duties as assigned

 Required Qualifications and Skills 

• Advanced degree (PhD, PharmD, RN, or equivalent) in a scientific or medical discipline preferred
• Minimum of 10 years of progressive experience in the biotech or pharmaceutical industry
• At least 3 years of hands-on experience in clinical trial planning, execution, and data analysis, preferably in a startup or growth-stage biotech environment
• Deep scientific knowledge with practical understanding of clinical development regulations in the U.S. and EU
• Demonstrated ability to lead the design, execution, and scientific oversight of clinical studies
• Extensive knowledge of GCP, ICH guidelines, trial methodology, and protocol development
• Experience contributing to regulatory documents (e.g., INDs, CSRs, IBs, DSURs)
• Strong analytical skills and the ability to interpret and communicate clinical and statistical data effectively
• Excellent written and oral communication skills across technical and executive audiences
• Strong organizational and project management skills with ability to prioritize and manage multiple timelines
• Effective in cross-functional environments, including clinical operations, biostatistics, regulatory, and external partners
• Self-starter with a demonstrated ability to work independently and take ownership of key initiatives
• Prior experience with infectious diseases preferred
• Background in orthopaedic or operative product development preferred
• Experience contributing to both early-stage (IND-enabling) and late-stage (BLA/NDA-enabling) programs preferred
• Familiarity with working in partnerships or across global teams preferred
• Experience supporting scientific publications or delivering presentations at scientific conferences preferred

Our Commitment to Equal Opportunity

Peptilogics is proud to be an equal opportunity employer. We make hiring decisions based on qualifications, experience, and potential—without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other protected status. We welcome candidates from all backgrounds to apply.