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Senior Scientist, Assay Development

Fremont, CA

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Summary:

You will work with a world-class, dynamic team of scientists, software engineers, assay developers, product managers, and clients applying our cutting-edge cancer and immuno-oncology solutions. As a Sr. Scientist, you will contribute to the development of new protocols, optimize new and existing methods, as well as plan, execute, analyze, and interpret results from development projects and validation studies. You should be an energetic and hands-on individual who has the technical background to identify issues and find effective solutions. Your work will contribute to a new generation of genomics-based precision medicine products in immuno-oncology and cancer clinical trials, diagnostics, and therapeutics being used by pharma, biotech, hospitals and clinicians.

Days onsite: Monday - Friday

Responsibilities:

  • Perform feasibility experiments to support early research and new product development.
  • Design, execute and document development, equivalency, verification and validation studies.  
  • Develop protocols to support high throughput automation and manual recovery methods.
  • Collaborate with the Tech Transfer and Automation teams for the development and implementation of new products and automation solutions.
  • Support documentation efforts for laboratory procedures.
  • Provide training and troubleshooting support for Operations end-users.
  • Work cross-functionally with the bioinformatics teams to plan experiments and analyses.
  • Participate in group meetings and present experiment results.
  • Use effective two-way communication to create and maintain a collaborative working environment.
  • Support and ensure compliance with all department and company policies and procedures

Requirements:

  • PhD with a minimum of 4 years of experience or MS with a minimum of 8 years of experience.
  • Minimum of 2 years of laboratory experience with NGS technology and RNA/DNA manipulation.
  • Strong written and verbal communication skills required.
  • Excellent organization and troubleshooting skills required.
  • Flexibility, multitasking, teamwork and self-initiative are required to support simultaneous projects.
  • Experience in biotech, clinical labs, lab automation, LIMS and/or bioinformatics is highly desired.
  • Strong desire to work in a demanding, high-energy, hands-on startup environment.

The hiring range for this position is $132,000 to $165,000 per year, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

 

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.

 

Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.) 

 

#LI-KK1 #LI-Onsite

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