Sr. Manager, Financial Internal Audit

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Position Summary:

The Financial Internal Audit, Sr. Manager plays a critical leadership role in safeguarding the company's assets and ensuring the reliability of financial reporting. This individual is responsible for planning, executing, and finalizing complex financial and operational audits, with a strong focus on Sarbanes-Oxley (SOX) compliance and internal controls. The Sr Manager will manage the audit lifecycle, mentor junior staff/outside consultants, and communicate critical risk and control findings to executive leadership.

Hybrid - Days Onsite: Mon/Tues

Key Responsibilities:

• Audit Planning & Management: Develop the annual internal audit plan based on risk assessments and coordinate all audit fieldwork, including resource allocation, budget management, and timeline adherence.
• SOX Compliance Oversight: Lead the annual Sarbanes-Oxley (SOX) compliance program, including scope definition, control testing, deficiency evaluation, and remediation tracking.  Maintain/update existing control narratives and/or develop new controls to support growing business needs.
• Execution & Review: Oversee and execute complex audits of financial processes (e.g., record-to-report, order-to-cash, payroll, treasury, etc.). Review testing workpapers and final reports prepared by junior staff/outside consultants.
• Risk Assessment: Proactively identify and evaluate key financial and operational risks across the organization, developing tailored audit procedures to address those risks.
• Stakeholder Communication: Serve as a primary liaison between Internal Audit, external auditors, and senior management across Finance and Operations to discuss audit findings, negotiate remediation plans, and monitor progress.
• Process Improvement: Recommend and drive efficiency improvements in corporate financial processes, controls, and overall risk posture.
• Leadership: Supervise, train, and mentor junior staff/outside consultants, fostering a high-performance culture focused on critical thinking.
• Other duties as assigned.

Required Qualifications:

• Education: Bachelor’s degree in Accounting, Finance, or a related field. Master’s degree preferred.
• Experience: Minimum of 7-10 years of progressive experience in internal audit, public accounting (Big Four preferred), or financial risk management.
• Certification: Active and valid professional certification is highly preferred (e.g., CPA—Certified Public Accountant, CIA—Certified Internal Auditor, or CISA—Certified Information Systems Auditor).
• Technical Expertise: Deep, practical expertise in U.S. GAAP and SOX 404 requirements.
• Skills: Proven ability to manage multiple complex projects concurrently, strong analytical and project management skills, and exceptional written and verbal communication abilities.

The hiring range for this position is $175,000 to $210,000 per year, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.

Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.) 

 

#LI-KK1 #LI-Hybrid