Job Application for Principal Scientist (Bioanalytical) at Precision for Medicine

Precision for Medicine is the first global precision medicine clinical research services organization, purpose-built to improve the clinical research and development process for new therapeutics. Our novel approach integrates clinical operations excellence, with laboratory expertise, and advanced data sciences to inform every step. We apply our expertise to trials at all stages—from early development through approval—with embedded experience in oncology and rare disease. With over 2000 dedicated professionals and 35 offices worldwide, we stand ready to help accelerate life-changing treatments anywhere around the globe. Won’t you join us today as a Principal Scientist, Bioanalytical?

Position Summary:

The Principal Scientist supervises laboratory staff to support bioanalytical activities. Lead Bioanalysis and Biomarker projects through assay design and development, validation, and execution in a timely manner. Perform assays according to SOPs and support technology development in Ligand Binding platform.

Essential functions of the job include but are not limited to:

Design and perform experiments, independently and accurately analyze and present data
Provide high quality output with the ability to build efficiency into improving productivity metrics
Serve as Technical Lead in Ligand Binding Platform
Assist in establishing and improving all procedures and required SOP documentation
Responsible for assay trouble shooting and correcting routine scientific issues/problems
Identify, update and implement emerging laboratory techniques
Maintain and support lab safety practices and environment
Work collaboratively with other technical teams in resource sharing and providing technical expertise
Support new equipment operational qualifications and performance checks
Monitor Lab Service/R&D related project expenses
Act as a scientific resource externally to clients and internally
Assists with writing, reviewing and editing contract and grant applications/proposals as appropriate
Assist with writing and publishing papers, abstracts, techniques/or chapters to maintain the scientific standard and image of the company.
May present completed work at appropriate scientific meetings and in publications
Supervision of assigned laboratory staff to ensure efficient organization, development and execution of project(s)
Other duties as assigned

Qualifications:

Minimum Required:

Must have a Ph.D. in life sciences or relevant field in life sciences
At least 8 years of full-time post-doctoral laboratory experience

Other Required:

Strong background in various technology platforms such as Mesoscale Discovery, Quanterix, Luminex, ELISA.
Ability to troubleshoot and refine bioanalysis and biomarkers assays such as ADA, PK, Potency Assay, Cytokine and PD biomarker measurement
Experience in handling various sample matrix such as whole blood, plasma/serum, cell pellets/supernatant, urine and CSF
Excellent communication, interpersonal, and organizational skills required.
Must have the ability to organize and analyze data, as well as prepare technical reports.
Must possess strong computational skills, preferably experienced with Softmax, MSD BenchWork, Word, Excel, Power Point, GraphPad Prism
Excellent use of judgment and discretion required
Extended work hours may be occasionally necessary in order to meet business demands
Ability to lift and carry between 1-15 lbs.; Ability to lift up to 50 lbs. overhead with assistance; frequently required to sit, grasp, and use right/left finger dexterity; May be exposed to a cold freezer environment (Freezer temperatures range between -20ºC -196ºC)
Must be able to read, write, speak fluently and comprehend the English language

Preferred:

A solid understanding of current bioanalytical method validation standards
Experience supervising or mentoring scientists or technical personnel
Previous work experience in GLP or GCLP or CLIA regulatory compliance

Precision is required by law in some states or cities to include a reasonable estimate of the compensation range for this role. This compensation range takes into account the wide range of factors that are considered in making compensation decisions including but not limited to: skill sets, experience and training, licensure and certifications, and other business and organizational needs. The disclosed range estimate has not been adjusted for the applicable geographic differential associated with the location at which the position may be filled. At Precision, it is not typical for an individual to be hired at or near the top of the range for their role and compensation decisions are dependent on the facts and circumstances of each case. This role is also eligible for a discretionary annual bonus, health insurance, retirement savings benefits, life insurance and disability benefits, parental leave, and paid time off for sick leave and vacation, among other benefits.

Reasonable estimate of the current range

$134,000 - $183,000 USD

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Principal Scientist (Bioanalytical)

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