Job Application for Research Associate at Precision for Medicine

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Aufgaben und Verantwortlichkeiten

Planung, Design, Durchführung, Etablierung, Analyse und Validierung bioanalytischer Experimente auf Basis von Ligandenbindungs-Assays (LBA), einschließlich Pharmakokinetik-(PK)-, Anti-Drug-Antibody-(ADA)-, Total-Antibody-(TAb)- und Neutralizing-Antibody-(NAb)-Studien, gemäß vorgegebenen Anweisungen zur Methodenentwicklung.
Durchführung biologischer Probenanalysen unter Anwendung etablierter und qualifizierter Ligandenbindungs-Methoden.
Eigenständige Einarbeitung in relevante Dokumente sowie Sicherstellung der Einhaltung aller geltenden Anforderungen und Richtlinien.
Analyse und Auswertung von Ergebnissen mithilfe von Precision Laboratory Information Management System (LIMS), Microsoft Excel und GraphPad Prism.
Unterstützung von Prozessen im Zusammenhang mit dem Laboratory Information Management System (LIMS).
Zusammenstellung und Aufbereitung von Ergebnissen für Übersichten, Entwicklungsfortschritte, Präsentationen und weitere Dokumentationsformate.
Prüfung von studien- und abteilungsbezogenen Dokumenten, z. B. SOPs, Validierungsprotokollen, Validierungsberichten, Notes-to-File, LIMS-Experimentprotokollen, Protokollvorlagen und Formularen.
Wartung von Laborgeräten sowie Übernahme der Verantwortung für zugewiesene Geräte.
Verantwortung für die Autoklavierung von flüssigen und festen Laborabfällen.
Verwaltung von Reagenzien bei unterschiedlichen Lagertemperaturen, Pflege des Material- und Reagenzieninventars für alle Projekte sowie Unterstützung bei Bestellprozessen.
Pflege und Aktualisierung klinischer Probendaten in den entsprechenden Systemen.
Mitwirkung bei der Erstellung, Optimierung und Einhaltung von Verfahren sowie erforderlicher SOP-Dokumentation für PK- und ADA-Methoden sowie weiterer abteilungsbezogener Dokumente.
Sicherstellung der Einhaltung von Labor-, Umwelt-, Gesundheits- und Sicherheitsvorschriften (EHS) sowie aktive Unterstützung entsprechender Sicherheitsmaßnahmen.

Anforderungsprofil

Abgeschlossenes Studium in Biologie, Biochemie, Biotechnologie, Pharmazie, Chemie oder einer vergleichbaren naturwissenschaftlichen Fachrichtung.
Erste Erfahrung im Bereich Bioanalytik oder Ligandenbindungs-Assays (LBA) von Vorteil.
Kenntnisse in PK-, ADA-, TAb- und/oder NAb-Analysen sind wünschenswert.
Erfahrung im Umgang mit LIMS-Systemen, Microsoft Excel und GraphPad Prism.
Sorgfältige, strukturierte und qualitätsorientierte Arbeitsweise.
Gute Team- und Kommunikationsfähigkeiten.
Sehr gute Deutsch- und gute Englischkenntnisse in Wort und Schrift.

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Research Associate

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