Spring 2025 Co-op: On-Target NGS

Company Overview:

Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.  

Prime Medicine is currently progressing a diversified portfolio of eighteen programs initially focused on genetic diseases with a fast, direct path to treating patients or with a high unmet need because they cannot be treated using other gene-editing approaches. Over time, the Company intends to maximize Prime Editing’s therapeutic potential and advance potentially curative therapeutic options to patients for a broad spectrum of diseases. For more information, please visit www.primemedicine.com.

Co-Op Assignment Overview

Prime Medicine is seeking a co-op for the Spring 2025 semester with experience in Molecular Biology to join the Next-Gen Sequencing (NGS) team. The candidate will be involved in a highly collaborative project team to streamline and automate portions of the NGS workflow at Prime Medicine. In this position, you will learn the principles of and lab techniques for NGS, while gaining experience with high-throughput automated systems and automated protocol development.

We are looking for a driven team member who is passionate about bettering human health by developing technologies that enable the discovery of genetic medicines.

Primary Responsibilities:

• Set-up and execute automated NGS library preparation workflows
• Perform manual quality control of NGS libraries
• Assist with development an automated NGS QC workflow to streamline the manual process
• Operate Illumina sequencers
• Analyze and interpret NGS quality and sequencing data to drive decisions in the development process for the automated QC workflow

Qualifications:

• B.S. candidate in Molecular Biology or related major
• Experience with Molecular Biology lab techniques such as PCR set-up
• Basic knowledge of NGS principles
• Excellent troubleshooting and communication skills
• Ability to work independently and within a team

Preferred Qualifications:

• Hands-on experience with NGS sample preparation or sequencer operation
• Familiarity with lab automation equipment
• Excellent problem-solving skills

What We Offer:

• A cutting-edge team open to mentorship and networking.
• Full reimbursement for monthly commuting costs including MBTA, Commuter Rail, or Bluebikes, etc.
• Participation in regular seminars with industry experts.
• Full participation in employee activities including learning and development offerings, social activities, etc.

NOTE: We are currently not considering co-op candidates outside of the local Boston/Cambridge area.

Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.