Spring 2025 Co-op: Screening Platform
Company Overview:
Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.
Prime Medicine is currently progressing a diversified portfolio of eighteen programs initially focused on genetic diseases with a fast, direct path to treating patients or with a high unmet need because they cannot be treated using other gene-editing approaches. Over time, the Company intends to maximize Prime Editing’s therapeutic potential and advance potentially curative therapeutic options to patients for a broad spectrum of diseases. For more information, please visit www.primemedicine.com.
Co-Op Assignment Overview
Prime Medicine is seeking a co-op for the Spring 2025 semester with experience in molecular biology to join the Screening Platform team. The candidate will be involved in leveraging automation systems for the development and execution of high-throughput screening for prime editing.
We want curious problem solvers who enjoy working with a team on exciting projects and are passionate about developing genetic editing technologies to better human health and well-being.
Primary Responsibilities:
- Use automated and semi-automated systems to select prime editing candidates for advancement toward therapeutic development pipelines
- Assist in the development and maintenance of immortalized and primary cell cultures
- Design, execute and troubleshoot high-throughput screens in immortalized and primary cells through the application of a variety of genetic perturbation methods
- Interpret and present data; provide key contributions that drive scientific strategy and shape cutting-edge therapies and technologies
Qualifications:
- Experience with molecular biology techniques such as nucleic acid purification, PCR, and NGS
- Basic understanding of molecular biology, cell biology, and biochemistry principles
- Proficiency in aseptic cell culture techniques
- Excellent troubleshooting and communication skills
- Ability to work independently within a team
Preferred Qualifications:
- Familiarity with CRISPR and other gene editing modalities
- Experience with high-throughput screening and/or liquid handling automation
- Experience with primary cell culture
What We Offer:
- A cutting-edge team open to mentorship and networking.
- Full reimbursement for monthly commuting costs including MBTA, Commuter Rail, or Bluebikes, etc.
- Participation in regular seminars with industry experts.
- Full participation in employee activities including learning and development offerings, social activities, etc.
NOTE: We are currently not considering co-op candidates outside of the local Boston/Cambridge area.
Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.
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