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Product Manager, AI

Chicago, IL

Who Are We?

Prolaio believes that continuous learning and collaboration can make a significant difference in how heart care is administered. We are creating smarter ways to address heart disease and heart risks by uniting patients, care teams, and researchers on a secure, technology-enabled platform that drives clinical innovation and offers a path towards better patient outcomes.

This is precision cardiology, and we know it’s within reach.

What Will You Do?

The Overview

The Product Manager - AI, Real World Data and Advanced Analytics will lead the definition and delivery of products that turn Prolaio’s cardiovascular data, clinical intelligence, and analytics capabilities into meaningful value for customers, partners, and internal teams. 

This role sits at the center of Prolaio’s mission to unlock continuous, predictive, and shareable heart data, translating clinical trial, real-world data, and healthcare workflow needs into differentiated product experiences, analytics capabilities, and insight-driven solutions that advance cardiovascular research, care, and therapeutic discovery.

The Specifics

  • Define and evolve the product strategy for AI, real-world data, and advanced analytics capabilities in alignment with Prolaio’s business goals, product roadmap, and mission in cardiovascular research and care.
  • Identify, prioritize, and shape product opportunities that leverage clinical trials data, real-world data, and advanced analytics to solve meaningful problems for external customers and internal stakeholders.
  • Develop clear product narratives, business cases, and prioritization frameworks for features and capabilities that strengthen Prolaio’s platform, product differentiation, and market impact.
  • Lead product discovery with internal and external stakeholders to define user problems, workflows, and outcome-focused use cases for AI, analytics, dashboards, and insight capabilities across the platform.
  • Create clear product requirements documentation (including common architecture backbone within the platform for AI features), user stories, acceptance criteria, and functional specifications that guide engineering (including RAG, bias and hallucination management, fairness monitoring, metadata intelligence), analytics, and data science teams in building the right solutions.
  • Drive product prototyping and iterative concept validation in partnership with design, engineering, analytics, and data science teams to test ideas early, refine requirements, and accelerate learning before full-scale build.
  • Serve as the product lead within agile delivery teams, partnering closely with Engineering and cross-functional stakeholders in sprint planning, standups, backlog grooming, and day-to-day decision-making to guide product development.
  • Lead sprint demos, release readiness, and post-launch feedback loops to ensure AI, real-world data, and advanced analytics capabilities are delivered with clarity, quality, and measurable user impact.
  • Envision and define analytics, reporting, and insight use cases that can be embedded within Prolaio’s platform and leveraged by both external and internal users, including clinical, operational, product, and commercial stakeholders.
  • Partner with Engineering, Data Science, Analytics, and Clinical Operations to translate user needs into product workflows, dashboards, data products, and AI-enabled features that are intuitive, actionable, and scientifically credible.
  • Lead the development of capabilities that use AI, real-world data, and advanced analytics to improve decision-making, trial execution, patient insights, and overall product value.

Why Prolaio?

  • Impactful Work: You will join in the fight against heart failure (HF) and hypertrophic cardiomyopathy (HCM) with the goal of extending and saving the lives of our patients while also being at the forefront of changing the healthcare industry through technology.
  • Innovative Environment: You will be part of an organization doing something that’s never been done before.
  • Professional Growth: You will join a growing team and have a substantial impact on our daily and future operations with the opportunity to continuously learn and grow.
  • Collaborative Team: You will be part of a team of collaborative, curious, and committed individuals focused on the collective good, inclusiveness, scientific excellence, and advancing digital health for cardiology.

Who You Are?

  • Bachelor's degree in a relevant field such as Life Sciences, Healthcare, Engineering, Computer Science, Data Science, Business, or a related discipline.
  • Minimum 5 years of experience in the healthcare industry, including at least 5 years in companies or environments focused on clinical trials, real-world evidence, real-world data, or real-world care settings as a Product Manager.
  • Demonstrated experience designing, developing, and delivering healthcare products that leverage clinical trials data, real-world data, and analytics capabilities.
  • Proven experience owning product discovery, product requirements documentation, prototyping, prioritization, and agile delivery for software, data, or analytics products.
  • Proven ability to define analytics and insights use cases for platforms or products that serve both external customers and internal stakeholders, and to translate those use cases into dashboards, workflows, and product capabilities.
  • Experience in developing wireframes and prototypes using tools like Figma, Lovable etc.
  • Experience in designing, developing and implementing privacy-enhancing techniques such as de-identification, tokenization, and pseudonymization in a data platform.
  • Experience working in a matrixed organization and partnering effectively with Product, Engineering, Clinical Operations, Analytics, Data Science, Quality, and Marketing teams to move products from concept to launch in regulated healthcare environments.

Why You’ll Love Working Here

  • Meaningful Compensation: Competitive salary, performance bonus, and equity so you can share in what we build.
  • Great Health Coverage: Medical, dental, and vision plans with multiple options and strong company contributions.
  • Flexible Spending Perks: HSA, FSA, commuter benefits, and a $1,200 annual Lifestyle Spending Account to support wellness, commuting, family needs, and more.
  • Time to Recharge: Generous paid time off, sick leave, and company holidays.
  • Family-First Benefits: Paid parental leave, caregiver leave, and support for growing families.
  • Security & Peace of Mind: Company-paid life insurance and short- and long-term disability coverage.
  • Plan for the Future: 401(k) plan to help you build long-term financial security.
  • Care When You Need It: Easy access to telehealth and optional supplemental coverage for life’s unexpected moments.

Starting Salary is at $159,000.00 (Exact Compensation may vary based on skills, experience, and location)

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