Back to jobs
New

Sr. Director, Data Engineering + Integrations

Chicago, IL

Who Are We?

Prolaio believes that continuous learning and collaboration can make a significant difference in how heart care is administered. We are creating smarter ways to address heart disease and heart risks by uniting patients, care teams, and researchers on a secure, technology-enabled platform that drives clinical innovation and offers a path towards better patient outcomes.

This is precision cardiology, and we know it’s within reach.

What Will You Do?

The Overview

The Director/Sr. Director, Data Engineering will lead and scale Prolaio’s healthcare data engineering capabilities that power its clinical intelligence products, real-world data pipelines, analytics, data science, clinical operations, quality, and data services in a regulated environment, building secure, reliable, and AI-enabled data platforms that transform continuous, predictive, and shareable heart data into faster therapeutic discovery and better cardiovascular outcomes while operating as a self-starter senior leader in a growth-stage company. This role will ensure that core data engineering features and services are built with security, privacy, compliance, and auditability by design, and other regulatory expectations relevant to Prolaio’s clinical and patient-data environment. This role will partner with colleagues in Product, Engineering, Quality, Clinical Operations to embed security, privacy, HIPAA and regulatory expectations into every layer of the data engineering features. This is a role for a self-starter and experienced engineering leader who brings both organizational leadership and strong technical credibility in designing, building, and continuously enhancing data engineering and AI-enabled data pipeline features in a growth-stage company.

The Specifics

  • Lead Prolaio’s enterprise data engineering strategy and roadmap to deliver secure, scalable, and reliable data platform capabilities aligned to clinical, research, product, and AI priorities in regulated healthcare settings.
  • Architect and oversee end-to-end data flows and reusable pipelines for ingestion, validation, transformation, enrichment, publishing, retention, archival, and decommissioning across batch, streaming, and hybrid workloads. 
  • Own the design and implementation of scalable, secure, and interoperable data platforms that support structured, semi-structured, and unstructured clinical, operational, device, and patient-generated data relevant to Prolaio’s cardiovascular mission. 
  • Define and enforce engineering standards for data modeling, lifecycle management, lineage, provenance, traceability, and auditability, embedding HIPAA, privacy, security, and GxP-aligned practices into day-to-day development workflows.
  • Partner closely with Data Architecture to design and govern conceptual, logical, and physical data models, apply healthcare standards (e.g., HL7, FHIR, ICD, SNOMED CT, LOINC, RxNorm, OMOP, CDISC), and deliver analysis-ready, interoperable datasets. 
  • Build and evolve robust data engineering capabilities across modern cloud platforms (e.g., GCP, AWS, Azure) and data platforms (e.g., Snowflake, Databricks, BigQuery, Redshift, Synapse), including orchestration, metadata, APIs, and integration patterns. 
  • Lead the development of AI-enabled data engineering features such as intelligent data quality monitoring, metadata enrichment, semantic search, feature generation workflows, and automation that accelerate analytics, data science, and clinical research teams.
  • Collaborate with Quality, Clinical Operations, Security, Product, and Engineering to embed validation, change management, governed data access, master data management, and release readiness into the data platform lifecycle.
  • Establish and manage high-performing data engineering teams, providing clear ownership, coaching, and execution discipline suited to a fast-moving growth-stage environment, while influencing architecture and implementation decisions across a matrixed organization.
  • Support vendor and tool evaluation, including build-versus-buy decisions for data integration, quality, metadata, lineage, interoperability, and AI-enabled data management capabilities.

Why Prolaio?

  • Impactful Work: You will join in the fight against heart failure (HF) and hypertrophic cardiomyopathy (HCM) with the goal of extending and saving the lives of our patients while also being at the forefront of changing the healthcare industry through technology.
  • Innovative Environment: You will be part of an organization doing something that’s never been done before.
  • Professional Growth: You will join a growing team and have a substantial impact on our daily and future operations with the opportunity to continuously learn and grow.
  • Collaborative Team: You will be part of a team of collaborative, curious, and committed individuals focused on the collective good, inclusiveness, scientific excellence, and advancing digital health for cardiology.

Who You Are?

  • Bachelor’s degree in computer science, Data Engineering, Information Systems, Biomedical Informatics, Engineering, or a related field.
  • Minimum 15 years of experience in healthcare, medtech, life sciences, digital health, or another patient-focused environment, with meaningful responsibility for data platforms, platform engineering, or cloud-native enterprise platforms. 
  • At least 7 years of experience as a Director or Sr. Director (or equivalent senior leadership role) leading data engineering or closely related data platform teams in growth-stage or innovation-driven organizations. 
  • Demonstrated experience architecting and delivering healthcare data platforms that support structured, semi-structured, and unstructured data, with proven success in regulated or validated environments. 
  • Deep understanding of healthcare data domains (clinical trials, cardiovascular and physiological data, real-world data, claims, medication, socio-economic and behavioral data) and the application of healthcare terminologies and common data models (e.g., HL7, FHIR, ICD, SNOMED CT, LOINC, RxNorm, OMOP, CDISC). 
  • Proven experience designing and operating end-to-end data flows, scalable pipelines, lineage, provenance, traceability, and data lifecycle management that support product, analytics, data science, clinical operations, quality, and data services use cases. 
  • Strong familiarity with cloud platforms such as GCP, AWS, or Azure and modern data platforms such as Snowflake, Databricks, BigQuery, Redshift, Synapse, or comparable environments, including hands-on work with orchestration, APIs, and integration. 
  • Strong software engineering and data engineering experience with Python and SQL and at least one of Java or .NET, with a track record of building internal data platform features, services, and developer tooling; experience with modern front-end frameworks (e.g., Angular or React) is good to have. Experience in developing Agentic pipelines would be a plus.
  • Demonstrated ability to work effectively in cross-functional, matrixed organizations, partnering with Product, Engineering, Data Science, Analytics, Clinical Operations, Quality, and Security, with a self-starter mindset and comfort with ambiguity in a growth-stage environment.
  • Familiarity with metadata, lineage, catalog, governance, and AI-enablement tools, including platforms for semantic indexing, vectorization, retrieval, and data lifecycle automation, and experience implementing governed data access and privacy-aware architectures.

Why You’ll Love Working Here

  • Meaningful Compensation: Competitive salary, performance bonus, and equity so you can share in what we build.
  • Great Health Coverage: Medical, dental, and vision plans with multiple options and strong company contributions.
  • Flexible Spending Perks: HSA, FSA, commuter benefits, and a $1,200 annual Lifestyle Spending Account to support wellness, commuting, family needs, and more.
  • Time to Recharge: Generous paid time off, sick leave, and company holidays.
  • Family-First Benefits: Paid parental leave, caregiver leave, and support for growing families.
  • Security & Peace of Mind: Company-paid life insurance and short- and long-term disability coverage.
  • Plan for the Future: 401(k) plan to help you build long-term financial security.
  • Care When You Need It: Easy access to telehealth and optional supplemental coverage for life’s unexpected moments.

Starting Salary is at $229,000.00 (Exact Compensation may vary based on skills, experience, and location

 

Apply for this job

*

indicates a required field

Resume/CV

Accepted file types: pdf, doc, docx, txt, rtf

Cover Letter

Accepted file types: pdf, doc, docx, txt, rtf

Select...
Select...
Select...
Select...

U.S. Standard Demographic Questions

We invite applicants to share their demographic background. If you choose to complete this survey, your responses may be used to identify areas of improvement in our hiring process.
Select...
Select...
Select...
Select...
Select...
Select...

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Prolaio’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Select...
Select...
Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Select...

Voluntary Self-Identification of Disability

Form CC-305
Page 1 of 1
OMB Control Number 1250-0005
Expires 07/31/2029

Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
  • Traumatic brain injury
Select...

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.