Scientist 1

At RefinedScience, our mission is to advance care by bringing together the best science, data and minds – disease by disease, patient by patient, cell by cell to discover pathways to life beyond disease.  

 

WHAT WE ARE LOOKING FOR

RefinedScience is seeking Scientist I to join an interdisciplinary team of computational biologists, data scientists, data engineers, cancer biologists, and clinicians who are seeking to develop new therapies, diagnostics, clinical decision support tools and optimize clinical trials for cancer and other diseases.

KEY ACTIVITIES

• The Scientist I will work directly with the Director, Translational Laboratory Research, CTO, CINO performing a wide range of cutting edge experiments to characterize specimens from patients to develop new therapies, diagnostics, clinical decision support tools and optimize clinical trials for cancer and other diseases.
• Utilize a variety of laboratory techniques required for research projects to perform experiments and tabulate and analyze research with below techniques:
• Isolation of rare blood and blood progenitor cells from bone marrow using magnetic bead separation and flow cytometry
• In vitro functional assays on human cells; maintenance of cell cultures
• Primer design and DNA/RNA manipulation
• Quantitative PCR
• Molecular cloning
• High throughput DNA sequencing
• Single cell technologies including library construction, quantification, and sequencing workflows
• Gene expression studies, including RNAseq and RNAi technology

• Provide laboratory science expertise and leadership in study design, study oversight, data management, data analysis and manuscript preparation to assist all levels of investigators, and researchers on new research activities across a wide range of disciplines
• Teach staff as needed, review relevant scientific literature, and attend and present at lab meetings
• Provide oversight on reagent purchases through management of budget and tracking of spending on specific projects, requiring in depth knowledge of nature of each individual project. Included in this duty is preparing a report of spending on projects and working with closely with administrative team to align budgets and spending.
• Assist with identifying issues related to operational efficiency and shares results with leadership
• Serve as a resource to PIs and other stakeholders
• Independently and creatively identify laboratory solutions
• Independently review, develop and implement new or modified laboratory techniques required for research projects
• Assist management with creation and implementation of processes and procedures and quality improvement initiatives
• Prepare lab for daily operations, including ordering, inventory, cleaning, and preparation of laboratory reagents
• Pick up, transport, and maintain results, samples, documents, materials and other items as needed
• The candidate will serve as lead on many of the above tasks including oversight and providing informal leadership to team members, including assistance in managing day-to-day priorities, and redistributing workloads, and mentoring staff. Will also lead in the identification of training and development opportunities for new and existing team members

 

MUST HAVES

• BS, MS, and/or PhD in Immunology, Molecular Biology, Cell Biology, or in a related discipline
• BS with 7+ years experience in a lab setting, MS with 3+ years, or PhD with 1+ years experience in a lab setting, either within an industry and/or academic setting

 

NICE TO HAVES

• Prior experience with cancer therapeutics, drug and clinical trial development.
• Prior experience with single cell technologies, flow cytometry, and working with human cells and tissues
• Familiarity with bioinformatics (i.e., computational, molecular, and cellular biology).
• Familiarity with quality assurance principles and activities (e.g. QMS), regulatory requirements (e.g., GDPR, HIPAA), and project management principles and tools (e.g., PMO, Slack, JIRA).

 

WHY YOU’LL LOVE REFINED SCIENCE 

Team + Values

At RefinedScience, we seamlessly integrate top-tier clinical and biological data with expert knowledge to provide unparalleled insights.  We maximize patient impact with these unique insights by optimizing clinical trial probability of success and time to actionable results. We work across biopharma and we are a trusted partner in achieving better results, faster – working together to unlock strategic advantage.

Our Values

• Act with Purpose – We believe in rigor through deliberate and thoughtful actions
• Be Curious – Curiosity is the spark that ignites innovation and growth
• Take Ownership – True ownership leads to pride and commitment in the work we do
• Invest in Relationships – Building strong connections is the foundation for effective collaboration and trust for long term success
• Embrace Agility – We celebrate agile thinking, resilience, and adaptability

 

WHAT WE OFFER

• The target salary range is $75,000 - $90,000 per year
• Base pay offered may vary within the posted range based on several factors, including but not limited to education, job-related knowledge, skills, experience, and location.