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Data Scientist II

Aurora, CO

Data Scientist II (remote)

At RefinedScience, our mission is to advance care by bringing together the best science, data and minds – disease by disease, patient by patient, cell by cell to discover pathways to life beyond disease.   

WHAT WE ARE LOOKING FOR

We are seeking a Data Scientist II with strong expertise in statistical modeling, machine learning, and real-world biomedical and electronic health records (EHR) data. The ideal candidate will apply advanced methods for empirical modeling and causal inference to support clinical research, health outcomes studies, and innovative trial designs.

KEY ACTIVITIES

  • Model Development and Innovation
    • Implement cutting-edge statistical and machine learning (ML) algorithms to solve complex biomedical, epidemiologic, and clinical problems.
    • Design and validate inferential and causal models to support hypothesis-driven research.
    • Develop and deploy reproducible models for analyzing large-scale clinical and real-world healthcare datasets.
  • Data Handling and Evidence Generation
    • Manage, preprocess, and transform structured and unstructured clinical data adhering to best practices in reproducibility and data integrity.
    • Investigate and conduct advanced data visualization and communication to enable scientific insight generation and stakeholder communication.
    • Generate real-world evidence (RWE) and clinical insights by evaluating model performance, uncertainty, and generalizability.
  • Cross-Functional Collaboration
    • Collaborate effectively with clinicians, key opinion leaders, researchers, data engineers, software developers, business stakeholders, and bioinformaticians to formulate clinical questions into actionable analysis plans and strategies.
    • Support and lead the writing of scientific manuscripts, abstracts, and technical reports.

QUALIFICATIONS

  • B.Sc. in Data Science, Mathematics, Statistics, Computer Science, Epidemiology, Biostatistics, or related field with 4+ years of relevant experience, OR
  • M.Sc. (or equivalent advanced degree) in a quantitative discipline with 1+ years of experience.
  • Strong proficiency in R, Python, and SQL (experience with Quarto or R Markdown/Shiny is preferred).
  • Applied experience with reproducible coding practices and package, function, and software development.
  • Proficiency in Linux, GitHub, and cloud platforms (AWS/GCP).
  • Hands-on experience with large-scale data processing pipelines and applied ML/statistical methods.
  • Excellent written and verbal communication skills for both technical and non-technical stakeholders.
  • Demonstrable problem-solving skills with evidence of tackling complex analytical challenges.
  • Proven ability to work in collaborative, multidisciplinary teams.

PREFERRED QUALIFICATIONS

  • Publication records in major journals, conferences, or scientific proceedings related to health-care informatics.

WHY YOU’LL LOVE REFINEDSCIENCE 

Team + Values

At RefinedScience, we seamlessly integrate top-tier clinical and biological data with expert knowledge to provide unparalleled insights.  We maximize patient impact with these unique insights by optimizing clinical trial probability of success and time to actionable results. We work across biopharma and we are a trusted partner in achieving better results, faster – working together to unlock strategic advantage.

Our Values

  • Act with Purpose – We believe in rigor through deliberate and thoughtful actions
  • Be Curious – Curiosity is the spark that ignites innovation and growth
  • Take Ownership – True ownership leads to pride and commitment in the work we do
  • Invest in Relationships – Building strong connections is the foundation for effective collaboration and trust for long term success
  • Embrace Agility – We celebrate agile thinking, resilience, and adaptability

WHAT WE OFFER

  • The target salary range is $110,000 to $135,000 annually. 
  • Base pay offered may vary within the posted range based on several factors, including but not limited to education, job-related knowledge, skills, experience, and location. 
  • We are interested in every qualified candidate who is eligible to work in the United States. However, we are not able to sponsor visas. 

BENEFITS

  • Medical, Dental and Vision insurance 
  • Life, AD&D, Short-term and Long-term Disability Insurance (none is 100% covered)
  • HSA Spending Accounts
  • 22 Vacation days
  • 10 Paid Holidays and Sick Time (120 hours per year)
  • 401(K) Plan

At RefinedScience, we believe diversity drives innovation. In order to commit to health for ALL PEOPLE and create positive impact, we’re building a culture where difference is valued. We take a holistic approach. We’re always growing our network of people, programs and tools all designed to help employees grow and manage their careers.

 

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