Scientist I/II, Integrative Biology (in vitro)
About Sail:
Sail Biomedicines is harnessing evolutionary and artificial intelligence to revolutionize programmable medicines. Sail’s platform combines first-in-class programmable RNA technology (Endless RNATM or eRNA), and an industry-leading platform of programmable nanoparticles, utilizing natural components, to unlock comprehensive programming of medicines for the first time. By leveraging cutting-edge eRNA and nanoparticle deployment technology, Sail is building a wealth of data, enabling unparalleled use of AI techniques to identify and design fully programmable medicines that are potent, targeted, versatile, and tunable. Sail was founded by Flagship Pioneering.
The Role:
We are searching for an innovative and highly motivated Scientist I/II to join the Integrative Biology group at Sail Biomedicines. Collaborating with an interdisciplinary team experienced in molecular biology, bioengineering, pharmacology, data science, and machine learning, this individual will develop and scale robust assays to discover the next generation of RNA medicines. The ideal candidate will bring a track record of scientific initiative and a deep commitment to teamwork to the Integrative Biology group’s fast-paced culture of scientific rigor.
Responsibilities:
- Help us build Sail’s core technological platform and discover novel therapeutics.
- Operate outside your scientific comfort zone to lead and support multiple projects from ideation through execution.
- Develop methods to assay the properties and performance of novel RNAs and Nanoparticles.
- Collaborate with automation scientists to scale assays for high throughput.
- Maintain impeccable documentation within Sail’s digital lab environment.
- Support the integration of machine learning into our science.
Necessary Qualifications:
- PhD in Nanotechnology, bioengineering or a closely related field or M.Sc. with 2+ years of experience working in either industry or academic research. (or equivalent combination of education and experience)
- Strong background in experimental design, data analysis, and interpretation.
- Effective communication with both technical and non-technical audiences.
- Proficiency developing assays from scratch and utilizing commercial bioassays.
- Ability to work effectively with minimal direction and oversight.
Desired Qualifications:
- Experience with lipid nanoparticles (e.g., particle formulation, chemical and biophysical characterization, and bio-molecule interactions).
- Experience developing high-throughput biochemical (e.g., Immunoprecipitation), molecular (e.g., qPCR), or cell-based assays (e.g., microscopy).
- Automation experience (e.g. liquid handlers).
Sail Biomedicines is an Equal Opportunity Employer. Sail does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, national origin, veteran status, or any other status protected under federal, state, or local law.
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