Scientist II - Histology

Location: South San Francisco, CA

Status: Regular Full-Time

Reports To: Associate Director, Gene Therapy

About SonoThera:

SonoThera is a venture capital-backed early-stage biopharmaceutical company developing ultra-sound-guided non-viral targeted gene therapies to treat multiple diseases of high unmet need. The Gene Therapy group at SonoThera uses a collaborative, interdisciplinary, and forward-thinking approach to solving many of the current challenges facing genetic medicine discovery and drug development. SonoThera is headquartered in South San Francisco, CA.

Job Description:

The Gene Therapy group at SonoThera is seeking to hire a Scientist II to become an integral part of the gene therapy drug development effort. We seek candidates who think critically and have the desire and ability to learn new techniques. This position requires adaptability and an ability to perform at a high level in a fast-paced environment. A qualified candidate will have broad technical experience in immunohistochemistry and image analysis. In this position, you will manage a team to characterize the delivery and expression of transgenic constructs in animal tissues and in vitro cellular models. You will Independently design and execute complex studies, analyze and interpret data, and communicate findings to both scientists and broad audiences. 

Qualifications:

• PhD degree in biological sciences (e.g. Molecular and Cell Biology, Pathology, Neuroscience or related field) with 3-5 years of relevant postgraduate research experience in an industry setting. 

• Demonstrated experience in overseeing and managing a high functioning team of biologists responsible for histological analysis of complex tissues. 

• Creativity and the ability to work within an interdisciplinary team to achieve technical and corporate milestones. 

• Strong verbal and written communication, critical thinking, and problem-solving skills. 

• Outstanding time management skills across multiple projects.

Technical Requirements and Skills:

• Initiate/lead complex projects and collaborate cross-functionally and/or externally. 

• Mentor more junior scientists in the lab and on project teams. 

• Strong technical expertise in histology, microanatomy, immunohistochemistry, RNAscope/ISH including expertise with quantitative image analysis (Visiopharm, HALO, Imaris, ImageJ, QuPath). 

• Previous experience using high-throughput methods including autostainers (i.e. Leica Bond) and slide scanners (i.e. Evident VS200).  

• Familiarity with research records keeping and sample management utilizing ELNs (i.e. Benchling).  

• Significantly contribute to patent filings, diligence reports, primary research publications, and/or regulatory documents. 

• Can expect to spend up to 30% of their time in the lab. 

Compensation: The salary range for this position is $120,000.00 to $150,000.00 USD annually. This salary range is an estimate, and the actual salary may vary based on various factors, including, without limitation, individual education, experience, tenure, skills, and abilities, as well as internal equity and alignment with market data, including potential adjustments for geographic location.

Benefits

At SonoThera, we'll give you the tools to feel healthy, happy and secure.

💰 Equity and ownership in a fast-growing company.

🏋🏻 Access to a 24-hour gym

💝 Comprehensive medical, dental, and vision

🚗 Commuting stipend based on your geographical location

🏦 401(k) Match: SonoThera offers a dollar-for-dollar match

🏝 All full-time employees are eligible for our flexible time off policy

 

Equal Opportunity for Diversity & Inclusion

SonoThera provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.