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Associate Scientist II, Vector Engineering

Boston, Massachusetts

Company Overview:

Strand Therapeutics is a clinical stage biotechnology company utilizing synthetic biology to genetically program mRNA to deliver truly revolutionary immunotherapies to patients.

Building on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological engineers working together at MIT who were seeking to apply the concept of the emerging field of mRNA therapeutics. Strand's technology is therapeutic-area and mRNA modality agnostic where therapeutic proteins are encoded onto modified, self-replicating, or circular mRNA backbones which in turn are programmed with cell-specific sensors and circuits.

Today, Strand has established three platforms with one clinical stage asset and several programs in preclinical development as well as early discovery. Our lead program, STX-001, is currently being evaluated in a phase 1 clinical trial for solid tumors. Our corporate headquarters is located in the Fenway district of Boston, Massachusetts.

Become the next standout single strand!

Job Summary:

Strand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a small but extremely productive team. This opportunity will offer the employee the ability to work in a matrix-based environment and be a part of the future strategy of the company.

We are looking for a highly motivated and innovative candidate for the role of Associate Scientist II of Vector Engineering. This is a fantastic opportunity to make a significant impact as a scientifically motivated self-starter capable of independently conceiving, conducting, and critically analyzing their own work with minimal supervision.

Primary Responsibilities:

  • Executing molecular cloning projects, including bacterial transformation and plasmid isolation.
  • Passage and maintain cell lines such as HEK293T and Jurkat cells and occasionally primary cells
  • Routine testing of synthetic genetic constructs with novel and optimized functions in mammalian cells using assays including flow cytometry and live cell imaging.
  • Ability to support high-volume requests for discovery and platform needs.
  • Assisting with data analysis, summarizing results in study reports, maintaining clear records in an electronic lab notebook, and providing updates at team meetings.
  • Working across diverse areas to support the group's research activities in a fast-paced and collaborative environment.

Qualifications:

  • B.S. or M.S. in biological sciences or related discipline.
  • 2-4 years of research experience in a biotechnology, pharmaceutical, and/or academic environment required.
  • Experience with mammalian cell culture of primary cells and cell lines required.
  • Experience with cellular and molecular biology techniques such as flow cytometry and molecular cloning is highly preferred with qPCR experience being a nice to have.
  • Hands-on experience with mRNA in vitro transcription is a plus.
  • Ability to write, edit, and follow standard operating procedures, make careful observations, maintain clear and complete records of lab work.

Strand offers a fast-paced, entrepreneurial, team-focused small company environment. We also offer a top-notch benefits package (health, dental, life, open PTO, onsite lunch catering, commuter support and more) and work/life flexibility and integration. Being part of the Strand team allows you to become part of a small team that supports professional development while working together to meet Strand’s goals. 

Strand Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Strand does not accept unsolicited resumes from any source other than directly from candidates.

Job Type: Full-time

Salary: commensurate with role and experience 

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