New

Associate Principal Scientist, PharmaR&D

Boston, MA

Are you passionate about using clinico-genomics to transform cancer therapeutic care?

Tempus is a technology company at the forefront of the expansion of multi-modal healthcare data generation and the application of artificial intelligence (AI) to fundamentally change cancer care.  Tempus is growing, and we are seeking exciting new talent to join the team.

Tempus' proprietary platform connects an entire ecosystem of real-world data to deliver real-time, actionable insights to physicians and drug developers.  As a Tempus employee you will have access to the world’s largest real-world patient clinical data set linked to genetics, transcriptomics and digital pathology. Our data empowers researchers to better characterize and understand disease, and to drive better outcomes through precise, individualized care.

The Associate Principal Scientist, PharmaR&D will design, propose and execute research projects for Tempus’s top biopharmaceutical partners.  This role will require staying up to date in research and industry trends in oncology drug development to identify specific areas where the Tempus platform can provide impact to our partners portfolio. This role involves performing complex computational analyses and guiding algorithm development for advancing cancer precision medicine for patients across the Tempus network.  The ideal candidate will possess strong genomic analytical skills, experience in applying machine learning and statistical models to big data, and the ability to communicate complex findings to various stakeholders.

Description

  • Scientific Communication: Expert in navigating client interactions; Present highly technical results and methods clearly and meaningfully to diverse sets of external stakeholders
  • Innovation: Drive continual improvement of the Tempus platform by integrating client feedback, staying ahead of research and industry trends, and championing new opportunities.
  • Collaboration:  Work with Research, Engineering & Data Science teams across Tempus’ expansive data science community to develop and deliver innovative computational solutions.
  • Drug R&D: Partner with big pharma clients.  Become proficient in the clients’ strategies, drug modalities and pipeline to identify where the Tempus platform can add value.  
  • Independent Contribution: Independently execute complex translational research projects integrating molecular and clinical data from Tempus’ multimodal data platform to extract insights and drive new research opportunities, including new target discovery.
  • Continuous Improvement: Stay current with industry trends, best practices, and advancements in computational oncology research. Apply this knowledge to enhance research methodologies and improve overall research quality 

 

 

Qualifications

  • Education and experience: 
    • Experience at a Pharmaceutical company or in a client facing analytical role
    • Either
      • PhD and additional 4+ years of working experience 
      • Masters and additional 6+ years of working experience
    • Combining:
      • Quantitative and computational skills (e.g. Computational Biology, Biostatistics/Statistical Genetics, Machine Learning, or Bioinformatics).
      • Biological or medical knowledge (e.g. Oncology, Immunology, or Human Disease).
      • Genomics and transcriptomics.
      • Target, drug or diagnostic discovery or clinical development.
  • Technical/Scientific Skills: 
    • Expertise in one of the following: in vitro data analysis, translational research, integrative analysis of multi-modal data, real world evidence and outcome analysis.
    • Proficient in R, Python, and SQL, and respective packages for computational biology. 
    • Strong understanding of cancer biology.
    • Applicable knowledge of machine learning and statistical modeling.
  • Communication Skills: 
    • Expert in navigating client interactions; Present scientific findings clearly and meaningfully to diverse sets of external stakeholders. 
    • Excellent written and verbal communication skills, with the ability to present complex information clearly and persuasively to diverse audiences. 
  • Motivated: Excel in a dynamic environment, seamlessly adapting to shifting priorities, and self motivated to explore portfolio related opportunities. 

 

Preferred Skillsets/Background

  • Goal orientation, self motivation, and drive to make a positive impact in healthcare.
  • Strong peer-reviewed publication record.
  • Previous experience working with large transcriptome and NGS data sets.
  • Ability to work collaboratively in a team environment
  • Experience with: RStudio, R Package development,  tidyverse, ggplot, Git, matplotlib, Pandas, Jupyter Notebooks

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

 

Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.

Apply for this job

*

indicates a required field

Resume/CV*

Accepted file types: pdf, doc, docx, txt, rtf

Cover Letter

Accepted file types: pdf, doc, docx, txt, rtf

Education

Select...
Select...
Select...
Select...
Select...
Select...
Select...

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Tempus’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Select...
Select...
Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Select...

Voluntary Self-Identification of Disability

Form CC-305
Page 1 of 1
OMB Control Number 1250-0005
Expires 04/30/2026

Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
  • Traumatic brain injury
Select...

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.