Scientific Affairs Manager

About Us

At Thesis, we believe that everyone has the capacity to unlock their brain’s full potential. In a world where technology is outpacing human evolution, it’s become more difficult to keep pace with the constant stimuli of the world we live in. The result? People are struggling to be present in every part of their lives. That’s why we’re building an ecosystem that helps people reclaim their focus, starting with nootropic blends to support every kind of brain.

Thesis helps people find the right nootropic blends for their brain chemistry—made from the highest quality, high potency and bioavailable blends at clinically studied dosages—to achieve their goals by boosting brain function and enhancing mental clarity. Thesis has already attracted significant attention, with over $14M raised in venture capital, endorsements from notable healthcare experts and athletes, and is advised by leading neuroscientists from Yale, Penn, and MIT. 

As we continue to grow, we’re looking for exceptional people to join us in revolutionizing cognitive enhancement. If you're ready to contribute to a pioneering movement that promises personal growth and industry leadership, we invite you to explore a career with us at Thesis. 

About The Role

We're seeking a Manager, Scientific Affairs to own scientific communications, consumer research, and ingredient strategy across Thesis and Stasis. This role sits at the intersection of science, regulatory, and storytelling—you'll translate complex research into compelling content for healthcare professionals, consumers, and internal teams while designing and running studies that inform product strategy. You'll serve as a thought partner on claims substantiation, study design, and product development, helping us build the scientific foundation for two growing brands.

How You'll Make an Impact:

• Develop white papers, science summaries, and educational content that communicate our research and ingredient science to internal and external stakeholders.
• Partner with Marketing to ensure scientific and regulatory accuracy in customer-facing content.
• Provide regulatory input during formulation development: GRAS status, ingredient feasibility, retail compliance considerations, and claims viability.
• Create reusable "science modules" that enable cross-functional teams to speak confidently about our products.
• Analyze ingredient literature to support new product development
• Create a pipeline of new ingredients for consideration in new product development and existing product reformulations
• Cultivate strategic partnerships with ingredient suppliers
• Build and maintain claims substantiation packets for all products, including evidence documentation, qualifiers, and approved marketing language.
• Design and program-manage studies end-to-end: protocol development, management, fielding, analysis, and stakeholder readouts.
• Build and maintain the Study Playbook (SOPs, templates, vendor processes) to systematize research operations.

We're Excited About Your:

• Bachelor’s degree (Master’s or Ph.D. preferred) in a relevant scientific field such as nutrition, food science, biology, chemistry, pharmacology, or a related discipline.
• 4+ years of experience in regulatory affairs, scientific research, or a related field, preferably within a regulated industry (e.g., supplements, food, pharmaceuticals, medical devices, biotechnology).
• Start-up experience strongly preferred
• Strong knowledge of regulatory frameworks (e.g., FDA, FTC).
• Excellent scientific writing skills
• Excellent analytical and problem-solving skills, with the ability to interpret complex scientific data.
• Exceptional written and verbal communication skills.
• Proactive ownership mentality with comfort operating in ambiguity.
• Highly organized and detail-oriented, with the ability to manage multiple projects simultaneously.
• Proactive and self-motivated with a strong commitment to excellence.
• Collaborative team player with a willingness to learn and adapt to new challenges.
• Ethical and professional in handling sensitive information.

Pay Transparency:

We can’t quantify everything we think you’ll love about working at Thesis, from the exciting projects you’ll work on, to the smart and humble team you’ll get to work with, and our supportive and inclusive culture. That said, our salary ranges are based on paying competitively for our size and industry, and are one part of our total rewards package, which also includes comprehensive benefits and equity. The base salary hiring range for this position is $100-135k base, but the final compensation offer will ultimately be based on the candidate’s location, skill level and experience.

A Few of Our Perks and Benefits:

• 💵 Competitive compensation with an exceptionally generous equity package
• 🩺 Competitive Health, dental, and vision plans (including a 100% covered premium plan for all 3!)
• 🚆 HSA, FSA and pre-tax commuter benefits for parking and transit
• 🚀 Ancillary benefits through Talkspace, One Medical, Kindbody, Teladoc, Classpass and more!
• 📈 401k to help you plan for the future
• 🏖 Flexible PTO because we respect the need for work/life harmony
• 🏋️ $100 monthly wellness stipend for your wellbeing (e.g. massage, cryotherapy, psychedelic therapy, etc.)
• 💊 Unlimited (yes, unlimited) Thesis nootropics
• 🎓A strong emphasis on promoting from within and personal development
• 🐕 A dog-friendly office located in the heart of Flatiron steps from Union Square and Madison Square Park
• 🏢 Hybrid work model

Our Values:

• Meet Your Potential: At Thesis, we create opportunities for personal and professional growth. We reward hard work, dedication, and an entrepreneurial spirit. We believe in open and honest feedback to help us continually learn and improve. In return, we are committed to providing the resources, support, and guidance for our team to achieve their ambitions and meet their potential. 
• Own Outcomes: We are driven by achieving meaningful results, both for our customers and our business. We’re proactive, conscientious, and take responsibility equally in times of triumph and challenge. We also operate with a sense of urgency because we want to seize the opportunity to create a new category and bring nootropics to everyone who needs them.
• Lead with Science and Data: We are obsessed with data to understand our impact, and always seek the truth through objective metrics that help us make informed decisions. Science and evidence underpin everything we do, from product formulation to marketing claims. We’re committed to making the highest quality nootropics on the market and measuring our efficacy.
• Create Exceptional Experiences: We are committed to creating a work environment that fosters a unique culture and deep sense of belonging. We create exceptional experiences by showing up for each other, giving each other the benefit of the doubt, and building an inclusive and warm environment—in and outside of the office. We’re equally committed to showing up for our customers by delivering a thoughtful and impactful experience for anyone who tries one of our products.