Scientist II, Animal Model Development

About Tonix*

Tonix is a fully integrated biotechnology company, publicly traded on NASDAQ (ticker: TNXP), with marketed products and a pipeline of development candidates The Company is focused on commercializing, developing, discovering, and licensing therapeutics to treat and prevent human disease. In August 2025, Tonix received FDA approval for Tonmya™ (cyclobenzaprine HCl sublingual tablets), a first-in-class, once-daily, non-opioid treatment for fibromyalgia. Tonmya is the first new fibromyalgia therapy approved in over 15 years, following successful Phase 3 trials demonstrating significant symptom improvement. Commercial launch is expected in the fourth quarter of 2025. Tonix also markets Zembrace® SymTouch® (sumatriptan injection) 3 mg and Tosymra® (sumatriptan nasal spray) 10 mg, both indicated for the treatment of acute migraine with or without aura in adults.

Tonix’s development portfolio includes product candidates in central nervous system (CNS), immunology, immuno-oncology infectious disease and rare disease. The CNS pipeline features both small molecules and biologics to treat pain, neurologic, psychiatric, and addiction conditions. The immunology portfolio includes biologics to address organ transplant rejection, autoimmunity, and cancer. The infectious disease pipeline includes a vaccine in development to prevent smallpox and monkeypox, which also serves as a live virus vaccine platform for other infectious diseases. Finally, the rare disease portfolio includes a product in development for Prader-Willi syndrome, which has both orphan drug designation and rare pediatric disease designation grants from the FDA.

Tonix owns and operates a state-of-the art infectious disease research facility in Frederick, Md.

Please visit www.Tonixpharma.com for specifics on the pipeline.

*All of Tonix’s product candidates are investigational new drugs or biologics and have not been approved for any indication.

Position Overview

Tonix Research and Development Center is seeking an experienced Scientist with expertise in novel animal model development for immunologic and infectious diseases, oncology, biological and vaccine development in order to advance the pipeline of novel therapeutics and vaccines in Tonix’s preclinical research portfolio.  The successful candidate will leverage their extensive experience in in vivo research to design, implement, and validate translational animal models, integrate advanced physiological monitoring tools, and ensure the highest standards of biosafety and personnel safety in the laboratory.

Key Responsibilities

Animal Development & Research 

• Lead the design, development, and standardization of innovative animal models for various disease indications such as autoimmune and oncology, supporting Tonix programs such as TNX-4200, TNX-4300, TNX-1500, TNX-1700, TNX-801, and other pipeline programs.
• Develop models that closely replicate human disease to support translational research and regulatory submissions.
• Evaluate and compare exposure and administration routes (intramuscular, intravenous, intratracheal, intrabronchial, tumor implantation, etc.) for pathogenesis, efficacy, and safety testing.
• Integrate telemetry, plethysmography, imaging, tumor growth monitoring, and other advanced physiological monitoring technologies into animal studies.
• Conduct natural history, proof-of-concept, survival, and pathogenesis studies under regulatory-compliant conditions.
• Conduct test article efficacy evaluation, pharmacokinetics/pharmacodynamics, and toxicologic studies in support of investigational new drug enabling activities throughout Tonix’s portfolio

Necessary Skills and Abilities

• Demonstrated expertise in developing and standardizing models which mimics human diseases such as infectious diseases and disorders of immune system,
• Proficiency in microbiological, immunological, and molecular assay techniques (e.g., ELISA, plaque assays, RT-PCR, flow cytometry).
• Experience as a PI or Study Director for in vitro and animal experiments.
• Strong technical writing, presentation, and data analysis skills.

Educational and Experience Requirements

• M.S. in Biotechnology, Biology, or related life sciences discipline (Ph.D. preferred).
• Minimum 10 years’ experience in biomedical research 

*Please note that Tonix does not offer sponsorship for this role.

Recruitment & Staffing Agencies

Tonix does not accept agency resumes unless contacted directly by internal Tonix Talent Acquisition. Please do not forward resumes to Tonix employees or any other company location; Tonix is not responsible for any fees related to unsolicited resumes.

Compensation & Benefits

Tonix provides a comprehensive compensation and benefits package which includes:

• Medical, Dental & Vision Insurance, Basic and Voluntary Life and AD&D Insurance, Short- and Long-Term Disability Insurance, Flexible Spending Accounts, Health Savings Account, and Employee Assistance Programs
• Pet Insurance
• Retirement Savings 401k with company match and annual discretionary stock options
• Generous Paid Time Off, Sick Time, & Paid Holidays
• Career Development and Training

Tonix provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, genetics, or any other characteristic protected by law.  In addition to federal law requirements, Tonix complies with applicable state and local laws governing nondiscrimination in employment.  This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfers, leaves of absence, compensation, and training.  Tonix expressly prohibits any form of workplace harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic, information, disability, veteran status, or any other characteristic protected by law.