Job Application for Senior Network Systems Architect at Ultragenyx Pharmaceutical

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Why Join Us?

Be a hero for our rare disease patients

At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won’t go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them.

Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth – so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work.

If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team.

Position Summary:

We are seeking a seasoned Network Systems Architect to lead the evolution of our global hybrid network and systems infrastructure. This role requires a strong foundation in Cisco Meraki, Azure Cloud networking, and Cisco ASA. The ideal candidate will bring hands-on expertise in designing, scaling, and supporting both on-premises and cloud environments, while contributing to a secure, reliable, and high-performing enterprise network.

Familiarity with automation tools such as Python, Terraform, and Ansible is preferred, but not mandatory for success. Experience working with Managed Service Providers (MSPs) and global telecom carriers to negotiate contracts and provision circuits is essential. This position combines architecture with day-to-day operational support, requiring a balance of strategic planning and practical execution.

ultracurious – Apply your biggest ideas in courageous ways

Work Model:

Flex: This role will typically require onsite work 2-3 days each week, or more depending on business needs. In many locations, the business will set certain days each week that Flex employees are required to be onsite.

Responsibilities:

Manage day to day operations, Architect, deploy, and manage hybrid infrastructure environments using Cisco Meraki, Azure networking services, and Cisco ASA firewalls

Design and templatize scalable Meraki configurations and maintain consistent deployment practices across locations

Create and maintain Hub-and-Spoke network architectures across Azure regions, ensuring resiliency, segmentation, and traffic control

Provide a solid understanding of routing protocols, Azure routing, UDRs, NAT gateways, VPN/ExpressRoute gateways, and NVA-based architectures with multi-region failover support

Develop and maintain architectural documentation including high-level designs, topology diagrams, and operational procedures

Support operational excellence by serving as an escalation point for L1/L2/L3 network and systems issues and ensuring timely resolution

Perform deep packet inspection and network troubleshooting using tools like Wireshark and NetFlow

Participate in the planning, procurement, and provisioning of global circuits, including direct engagement and negotiation with carriers and service providers

Collaborate with MSPs and internal teams to manage operations, incidents, capacity planning, and global deployments

Familiar with automation tools such as Python, Terraform, and Ansible to streamline network and systems workflows

Utilize tools like ThousandEyes, Azure Monitor, and log analytics to ensure observability and proactive incident response

Ensure strong cross-functional collaboration with IT security, infrastructure, and compliance teams

Support growth and scaling initiatives by addressing evolving infrastructure needs, integrating new locations, and expanding global connectivity

Contribute to the recruitment, mentorship, and development of junior and mid-level engineers

Requirements:

10–15+ years of experience in network and systems architecture, with a blend of cloud and on-premises responsibilities

Strong hands-on experience with Cisco Meraki, Cisco ASA, and Azure Firewall, as well as Azure network design and deployment

Solid understanding of core networking concepts such as BGP, IPsec, and high-availability configurations

Demonstrated experience managing or collaborating with MSPs and supporting global operations

Experience negotiating with and provisioning circuits through global telecom carriers

Strong analytical and troubleshooting skills, especially in production environments

Comfortable handling operational demands, including incident response, change control, capacity planning, and documentation

Excellent communication and interpersonal skills, with experience engaging both technical teams and senior stakeholders

Ability to manage shifting priorities and infrastructure needs as the company grows and scales globally

Preferred Qualifications:

Bachelor’s degree in Computer Science, Engineering, or a related field, or equivalent work experience

Prior experience working in pharmaceutical or regulated industries

Working knowledge of Windows Server, Active Directory, DNS, DHCP, and group policy configurations and core systems operations

Experience with zero-trust network design, hybrid cloud security models, and compliance frameworks

Certifications such as CCNP, Azure Network Engineer Associate, or equivalent

#LI-CK1 #LI-Hybrid

Full Time employees across the globe enjoy a range of benefits, including, but not limited to:

· Generous vacation time and public holidays observed by the company

· Volunteer days

· Long term incentive and Employee stock purchase plans or equivalent offerings

· Employee wellbeing benefits

· Fitness reimbursement

· Tuition sponsoring

· Professional development plans

* Benefits vary by region and country

Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at talentacquisition@ultragenyx.com.

See our CCPA Employee and Applicant Privacy Notice.

See our Privacy Policy.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Note to External Recruiters: All candidate activity and open positions are managed strictly through our Human Resources Department. Our Human Resources Department kindly requests that recruiters not contact employees/hiring managers directly in an attempt to solicit business and present candidates. Please note that failure to comply with this request will be a factor in determining a professional relationship with our organization. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation. Inquiries on developing a recruiting relationship with us, may be directed to: talentacquisition@ultragenyx.com.

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We are dedicated to fostering an inclusive workplace environment that keeps our teams inspired, empowered, and free to share new ideas—and to better finding solutions that advance the treatment of those living with rare diseases. We invite you to voluntarily provide demographic information in a confidential survey at the end of this application to assist us in complying with legal requirements and managing our organization. Providing this information is completely optional and it will not be accessible or used by those involved in your hiring or decision-making process. Your response – or decision not to respond, has no impact on your opportunity for employment. Responses to the voluntary self-identification requests will be confidential and securely maintained and only reported in the aggregate in support of the efforts outlined above.

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Senior Network Systems Architect

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