Principal Scientist, DEL Data Analysis & Informatics
About Us
Valo Health is a human-centric, AI-enabled biotechnology company working to make new drugs for patients faster. The company’s Opal Computational Platform transforms drug discovery and development through a unique combination of real-world data, AI, human translational models and predictive chemistry.
Our talented team of biologists, chemists and engineers, armed with advanced AI/ML tools, work together to break down traditional R&D silos and accelerate the speed and scale of drug discovery and development.
Valo is committed to hiring diverse talent, prioritizing growth and development, fostering an inclusive environment, and creating opportunities to bring together a group of different experiences, backgrounds, and voices to work together. We embrace new ways of learning, solve complex problems and welcome diverse perspectives that can help us advance patient-centric innovation.
Valo is headquartered in Lexington, MA, with additional offices in New York, NY and Tel Aviv, Israel. To learn more, visit www.valohealth.com.
About the Role...
You will be responsible for advancing Valo Health by joining the DNA Encoded Library (DEL) team with a focus on data analysis. Your role will be to participate as part of a project team and analyze DEL data with an aim to achieving rapid and thorough project starts with high quality chemical matter. You will act as a platform champion for the DEL informatics platform – working with partners in a range of departments, including DEL, Medicinal Chemistry, Software Engineering & Chemical Data Science to identify needs and partner to create solutions. If you are interested in playing a critical role in driving the program progression at a mission-driven company that is setting out to revolutionize healthcare and the drug development process, Valo is the place for you.
What You’ll Do…
- Work as part of a multidisciplinary team to support internal and external drug discovery efforts
- As part of a project team work with DEL scientists, Medicinal Chemists & Data scientists to analyze DEL data and help launch drug discovery projects
- Champion the Valo DEL platform, at the interface of DEL synthesis, selections, data analysis, and machine learning
- Work as part of the DEL team to analyze DEL selection data in support of drug discovery programs
- As part of a team, continually improve the DEL informatic platform and design/suggest tools to increase efficiency, support DEL machine learning, and improve the user experience
- Act as a key connector and champion for the multidisciplinary workflow between data science, engineering, and discovery sciences
- Help enable informatics solutions that bridge between lab and data science workflows to vastly improve speed and quality of DMTA cycles through machine learning
- Work with Valo data scientists and engineers to improve our informatic drug discovery platform
What You Bring...
- A Ph.D. in chemistry, or a related field with 5-7 yrs experience (for M.S. 7-12 yrs experience and over 15 yrs experience for a BS)
- Demonstrated expertise with DEL platforms, selection data analysis, and hit identification
- Proven ability to act as a platform champion and interdisciplinary team member leveraging exceptional interpersonal & influence skills
- Demonstrated experience leading complex, multi-disciplinary projects from inception to delivery – defining project objectives, communicating progress & sprinting toward final delivery
- Strong understanding of data science and statistical approaches to drug discovery
- Familiarity with key programming languages and cheminformatics tools Python, Streamlit, ChemAxon, RDKit etc. and cloud based database applications (ie snowflake, AWS etc) experience is a plus.
- Experience working with machine learning applications in drug discovery is a plus
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