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Scientist II, Bioanalytics

San Francisco, California, United States

Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies. 

Vir Biotechnology has exclusive rights to the universal PRO-XTEN® masking platform for oncology and infectious disease. PRO-XTEN® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company.

We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best.

THE OPPORTUNITY

Vir Biotechnology is seeking a detail-oriented, highly motivated Bioanalytical Scientist to join our Translational Development team.

In this role, you will develop and implement bioanalytical methods to support large-molecule programs at both preclinical and clinical stages. Responsibilities include designing and executing immunochemistry assays (e.g., ELISA, MSD, anti-drug antibody assays) and preparing samples for LC-MS/MS analysis. You will contribute to immunoassay development across multiple programs and analyze preclinical samples for drug concentrations and anti-drug antibodies.

This description outlines the primary responsibilities and requirements but is not exhaustive; additional related duties may be assigned as needed.

This position is based at our San Francisco headquarters, with an expectation of at least 4 days per week on site.

WHAT YOU'LL DO

  • Develop and optimize bioanalytical methods to support large-molecule preclinical and clinical candidates, providing bioanalytical input across research and development stages.
  • Plan and coordinate method development and sample analysis activities in alignment with program and development timelines.
  • Troubleshoot and evaluate complex bioanalytical methods to identify and implement robust solutions.
  • Prepare and characterize assay reagents using standard biochemical techniques (e.g., protein conjugation, concentration determination, UV/Vis spectrophotometry).
  • Maintain thorough and timely documentation in electronic lab notebooks; compile, analyze, and interpret data.
  • Present experimental plans and results in group and cross-functional settings to communicate assay development progress.
  • Perform routine instrument maintenance, calibrations, and performance checks as needed.
  • Collaborate closely with other assay development team members to achieve project and departmental goals.

WHO YOU ARE AND WHAT YOU BRING

  • PhD with 1+ years, MS with 6+ years, or BS with 8+ years of relevant industry experience.
  • Experience that combines hands-on laboratory work with project oversight; prior experience managing CROs for clinical and nonclinical assay development/validation is a plus.
  • Demonstrated understanding of GLP/GCP principles as they pertain to sample handling and storage, bioanalytical assay development, sample analysis, and laboratory operations.
  • Strong technical expertise with platforms used to characterize large-molecule therapeutics, including assays with complex handling and preparation (e.g., enzymatic, ligand-binding, cell-based assays, and LC-MS/MS assays) across a range of biological matrices (e.g., serum, plasma).
  • Familiarity with PK/PD concepts and their application to assay design, selection, and range determination.
  • Prior work in GCP/GLP/GMP environments is advantageous but not required.
  • Prior work utilizing LC/MS/MS is advantageous but not required
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WHO WE ARE AND WHAT WE OFFER

The expected Salary range for this position is $116,000 to $146,000 per year. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors.

Vir Biotechnology's compensation and benefits are aligned with the current market and commensurate with the person’s experience and qualifications.

Applicants must currently be authorized to work for any employer in the U.S.  We are unable to sponsor or take over sponsorship of an employment Visa at this time.

All employment decisions at Vir Biotechnology are based on legitimate, non-discriminatory business requirements, job duties and individual qualifications. Employment decisions are made without regard to any legally protected characteristics. 

This commitment extends to all management practices and decisions, including recruitment and hiring, compensation, appraisal systems, promotions, training and career development programs.  Vir Biotechnology also strongly commits to providing employees with a work environment free of unlawful conduct or harassment.

Vir Biotechnology Human Resources leads recruitment and employment for Vir Biotechnology. Unsolicited resumes sent to the company from recruiters do not constitute any type of relationship between the recruiter and Vir Biotechnology and do not obligate us to pay fees should we hire from those resumes. We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring manager or employees.

For hires based in the United States, Vir Biotechnology, participates in E-Verify.

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