New

Senior/Director, Program Management

Boston

Join Us in Tackling Autoimmune Disease at Its Root

At Vor, we believe science can do more than manage symptoms. It can change the course of disease. By advancing telitacicept, a first- and potentially best-in-class dual BAFF/APRIL inhibitor, we are silencing upstream survival signals and stopping downstream autoimmune cascades. Together, we are addressing disease at its root cause and rewriting what is possible for patients worldwide.

When you join Vor, you’re not just working on a medicine. You’re part of a mission to redefine the future of autoimmune care.

Why Work at Vor?

Impact: Contribute directly to a medicine with best-in-disease Phase 3 results in myasthenia gravis and expansion into multiple autoimmune diseases.

Growth: Be part of a rapidly scaling company with opportunities to grow your career in science, clinical development, commercial strategy, and beyond.

Innovation: Work on a platform with potential beyond one indication — a therapy that has already shown consistent results across lupus, IgA nephropathy, and Sjögren’s syndrome.

Belonging: Join a culture where every voice is heard, and where our shared mission unites us across functions and geographies.

 

Who we are looking for

Vor Biopharma is seeking a highly motivated and experienced Director/Senior Director, Program Management to oversee the strategic and operational management of a late-stage clinical program in autoimmune diseases. This individual will provide leadership across cross-functional teams to ensure successful execution of Phase 3 clinical trials, regulatory interactions, and preparation for potential product launch.

The Director will play a pivotal role in aligning scientific, clinical, regulatory, and commercial strategies to drive the program forward in a fast-paced, small biotech environment.

Key areas of responsibility

Program Leadership

  • Lead the overall strategy and execution of a global Phase 3 clinical program in autoimmune diseases.
  • Serve as the accountable owner for program deliverables, timelines, and budget.
  • Ensure alignment of program objectives with company goals and long-term strategy.

Clinical & Regulatory Oversight

  • Partner with Clinical Operations, Medical, Regulatory, and Biostatistics teams to ensure Phase 3 trial execution meets quality, compliance, and regulatory standards.
  • Support preparation and submission of regulatory documents (NDA/BLA, briefing books, responses to regulatory queries).
  • Oversee interactions with the FDA, EMA, and other global regulatory agencies.

Cross-functional Collaboration

  • Lead cross-functional core teams (Clinical, Regulatory, CMC, Commercial, Medical Affairs) to ensure integrated program planning and decision-making.
  • Provide clear communication of program progress, risks, and mitigation strategies to executive leadership and the Board of Directors.
  • Collaborate with Commercial and Medical Affairs to prepare for launch readiness and market access planning.

External Partnerships

  • Manage relationships with CROs, investigators, advisory boards, and key opinion leaders in autoimmune diseases.
  • Represent the company at scientific conferences, investor updates, and industry meetings as appropriate.
  • Operational & Financial Management
  • Oversee program budgets, contracts, and resource planning.
  • Identify risks and proactively develop contingency plans to maintain trial integrity and timelines.

Qualifications

  • Advanced degree preferred (PhD, MD, PharmD, or equivalent in life sciences).
  • 12+ years of biotech/pharma experience, with at least 5 years in program or project leadership.
  • Proven track record leading late-stage (Phase 2/3) clinical programs, ideally in autoimmune or immunology-related indications.
  • Experience in regulatory submissions (NDA/BLA) and health authority interactions.
  • Demonstrated ability to thrive in a small-company, fast-paced environment with limited infrastructure.
  • Strong leadership, strategic thinking, and communication skills.

Competencies

  • Visionary leadership with hands-on execution ability.
  • Deep understanding of clinical development and regulatory pathways.
  • Excellent cross-functional collaboration and influence.
  • Entrepreneurial mindset and adaptability.
  • High integrity and commitment to patients and compliance.

 

 

 

At Vor, we support our team with robust benefits, including comprehensive health coverage, flexible paid time off, generous parental leave, and a competitive 401(k). From education assistance to wellness resources and financial security, we invest in your well-being so you can thrive at work and beyond.

As an equal opportunity employer, we at Vor Bio know that diversity inspires innovation, inclusiveness, and creativity. We invite you to come as you are. All applicants will be considered for employment agnostic to race, age, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

Please visit our website at https://www.vorbio.com/ for more information.

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