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Research Associate/ Senior Research Associate, Functional Genomics

About the Role

We are seeking an exceptional individual to join our High-throughput Biology team as a Research Associate / Senior Research Associate. The ideal candidate will have a proven track record of developing innovative molecular biology protocols to solve complex biological problems. We are looking for someone passionate about technique development who thrives in a fast-paced, innovative, and multidisciplinary environment. You will collaborate closely with biologists, bioinformaticians, chemists, and software and automation engineering experts to drive impactful research.

Key Responsibilities

  • Execute and optimize high-throughput single-cell perturb-seq experiments, including cell culture, cell engineering, genetic perturbation, and RNA-seq library preparation.
  • Collaborate closely with cross-functional scientists to troubleshoot protocols, improve workflow efficiency, and ensure high data quality.
  • Contribute to functional genomics technology development by testing and refining experimental methodologies to systematically explore gene function in disease contexts.
  • Maintain meticulous records of experimental procedures and results to support reproducibility and data integrity.
  • Present findings and updates in team meetings, fostering a collaborative approach to project advancement.

Qualifications

  • B.S./M.S. in Molecular Biology, Genetics, Bioengineering, or a related field with a minimum of 2 years of work experience in relevant areas.
  • Proficiency in cellular and molecular biology techniques, including cell culture, genetic perturbation (e.g. CRISPR), molecular cloning, qRT-PCR, Western blot, and immunostaining.
  • Hands-on experience with lentiviral techniques for gene delivery, including viral vector preparation, titration, and cell transduction.
  • Experience with single-cell sequencing or other high-throughput sequencing techniques is strongly preferred.
  • Ability to design and execute experiments with a critical approach, including planning, controls, and troubleshooting to generate reliable data.
  • Basic data analysis skills and familiarity with software tools for data interpretation; experience with bioinformatics or programming (e.g. R, Python) is a plus.
  • Strong attention to detail and ability to follow complex protocols with precision.
  • Excellent organizational and documentation skills, with the ability to maintain accurate and detailed lab records.
  • Strong communication skills and a collaborative mindset, with a desire to work within a dynamic, interdisciplinary team environment.
  • Ability to troubleshoot experiments independently and adapt to evolving research needs.

Compensation

The specific compensation package for this role depends on experience, qualifications and level. We anticipate the compensation range to be $60,000 to $111,000 per year. 

Xaira Therapeutics is an equal opportunity employer. We thrive on diversity and collaboration, and we welcome candidates with diverse backgrounds and experiences. 

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