Research Associate/Senior Research Associate

About Xaira Therapeutics

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

About the Role

We are seeking a Research Associate/Senior Research Associate to work with the Binder Discovery team to develop new therapeutic molecules. You have prior experience with either mammalian expression systems, flow cytometry and protein purification & characterization. You are a curious research associate who enjoys learning new techniques and optimizing protocols. You present results and summarize progress to help internal decision-making. Collaboration comes naturally to you, and you thrive in a fast-paced environment where pushing the boundaries of what is possible is the norm.

Key Responsibilities

• Perform and optimize antibody expression in mammalian cells
• Maintain up-to-date electronic lab notebooks and manage data
• Support the discovery and development of therapeutic molecules through hands-on laboratory work.
• Develop, document, and refine protocols to improve reproducibility and efficiency in experimental workflows.
• Conduct and analyze high-throughput assays to evaluate the functionality and binding properties of potential therapeutic candidates

Qualifications

• 2+ years of laboratory experience (industry experience preferred)
• Bachelors in Biochemistry, Structural Biology, Biology, or similar fields
• Demonstrated ability to improve protocols to yield more reproducible/improved results
• Experience with at least 1 of the following required:
• Transient transfections in mammalian cell culture (cell line maintenance, feed, etc)
• High throughput flow cytometry with 3 colors, or high throughput protein production
• Protein purification (Kingfisher, AKTA, HPLC) and QC (CE-SDS, HPLC, LC-MS, etc)
• Additional desired experience with (not required):
• High throughput protein production or assay development
• Liquid handling, robotics, and automation workflow
• ELN/LIMS, Benchling preferred
• Molecular biology (primer design, Gibson, Golden Gate, minipreps, sequence alignment)

Compensation

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. The base pay range for this position is expected to be $60,000 - $111,000 annually; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.

Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.

TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. Xaira Therapeutics is not responsible for any fees related to unsolicited resumes.