Director, Medicinal Chemistry

Our Mission

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.

For more information, see our website at altoslabs.com.

Our Value

Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.

Diversity at Altos

We believe that diverse perspectives are foundational to scientific innovation and inquiry. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment.

What You Will Contribute To Altos

An exciting opportunity is available for a talented Director/Senior Director to join the Institute of Medicine (IoM) Development Sciences team at Altos Labs.

We are seeking highly motivated, creative, and collaborative individuals who are passionate and dedicated to employing their expertise to restore cell health and reverse disease. This position will be part of a multidisciplinary team within the IoM to develop novel therapeutic projects at Altos. The candidate will work in a highly dynamic and cross-functional environment that requires collaboration with the Institutes of Science and Computation (IoS and IoC), and will span multiple therapeutic areas and therapeutic modalities. The successful candidate will have strong scientific training and experience in the biotechnology or pharmaceutical industry.

Responsibilities

•   Develop, optimize, and implement Medicinal Chemistry strategies and build infrastructure to support discovery programs
•   Lead and/or represent Medicinal Chemistry in multifunctional discovery and early development project teams.
•   Work with scientists at the Institutes of Science (Bay Area, Cambridge, San Diego) to design and synthesize tool molecules to explore biological and molecular mechanisms of action.
•   Effective cross-functional collaboration, especially with the IoS and IoC, in vitro/in vivo pharmacology, DMPK and toxicology, in the optimization of drug leads and candidates. 
•   Recommend, initiate, lead and champion innovations from external, global and local sources to ensure cutting-edge science is applied to project-related issues
•   Manage resource allocation, including leveraging CRO partners and internal resources in other Altos Labs groups as needed
•   Continuously assess assay capability and capacity needs based on the evolving pipeline at Altos
•   Create and foster strong partnerships with groups in the Institutes of Science and Medicine
•   Contribute to a team culture that promotes continuous improvement, ownership, professional growth, and inclusion

Who You Are

Minimum Qualifications:

• Ph.D. in Organic or Medicinal Chemistry with 10+ years of industry experience in Drug Discovery
• Extensive knowledge of medicinal chemistry and drug discovery approaches (e.g., structure-based design, computational chemistry, multi-parametric optimization of bioactivity/physicochemical/ADME properties)
• Experience working with CROs in outsourcing screening, chemical synthesis, and evaluation of compounds.
• Demonstrated track record of patents and publications in medicinal chemistry
• Demonstrated ability to partner and collaborate effectively with research teams and drug discovery functions.
• Clear and influential communicator: exceptional influencing skills that demonstrate strong thought partnership and create effective relationships with internal and external groups and individuals

Preferred Qualifications:

• Experience with oligonucleotide chemistry is desirable.
• Project leadership experience is highly desirable

We are open to considering candidates in either our Redwood City or our San Diego location. The full salary ranges by location and level are below.

The salary range for San Francisco Bay Area:

• Director: $278,000 - $377,200
• Senior Director: $316,200 - $427,800

The salary range for San Diego:

• Director: $250,750 - $339,250
• Senior Director: $294,950 - $399,050

Exact compensation may vary based on skills, experience, and location.

For UK applicants, before submitting your application:

- Please click here to read the Altos Labs EU and UK Applicant Privacy Notice (https://bit.ly/3fHGl98)
- This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.

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What We Want You To Know

We are a culture of collaboration and scientific excellence, and we believe in the values of inclusion and belonging to inspire innovation.

Altos Labs provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. 

This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training. 

Altos currently requires all employees to be fully vaccinated against COVID-19, subject to legally required exemptions (e.g., due to a medical condition or sincerely-held religious belief).

Thank you for your interest in Altos Labs where we strive for a culture of scientific excellence, learning, and belonging.

Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos. Learn more about a common job scam at https://www.linkedin.com/pulse/how-spot-avoid-online-job-scams-biron-clark/