Director/Senior Director, Supply Chain - Pleasanton, CA

Calyxo, Inc. is a medical device company headquartered in Pleasanton, California, USA. The company was founded in 2016 to address the profound need for improved kidney stone treatment. Kidney stone disease is a common, painful condition that consumes vast amounts of healthcare resources each year. Our team is led by executives and investors with a proven track record of commercializing paradigm-shifting devices to meet unmet needs within urology.

Are you ready to change the future of kidney stone treatment? We are seeking high achievers who want to be part of a dynamic team working in a fun, diverse atmosphere.

Summary: 

The Sr. Director of Supply Chain is responsible for developing and leading the company’s global supply chain strategy, encompassing procurement, logistics, planning, and inventory management to support business growth, operational excellence, and compliance within a regulated medical device environment. This role is instrumental in driving cross-functional alignment, supplier performance, cost optimization, and end-to-end process scalability as the organization expands. The ideal candidate brings deep supply chain expertise in the medical device industry, demonstrated success in executive-level leadership, and a track record of building world-class supply chain functions. This is an in-office position based in Pleasanton, CA. 

In This Role, You Will:

• Strategic Supply Chain Leadership: Develop and lead the execution of a comprehensive global supply chain strategy aligned with company goals, supporting scalability, innovation, and operational efficiency. 

• Inventory Optimization: Drive inventory strategy and planning processes to balance working capital and service levels across all product lines and manufacturing stages. 

• Supplier Strategy & Qualification: Lead global sourcing strategy and supplier management efforts in collaboration with R&D, Manufacturing, and Quality to ensure high-performing, compliant, and cost-effective partnerships. 

• Process Development & Scalability: Build and evolve supply chain processes and infrastructure to support growth, new product introductions, and global expansion, with a focus on long-term scalability and risk mitigation. 

• Cost Reduction & Operational Efficiency: Identify and lead strategic cost reduction initiatives, including supplier consolidation, contract negotiations, make/buy analysis, and low-cost country sourcing. 

• Performance Monitoring & Reporting: Define and manage robust KPIs and reporting frameworks to monitor supply chain effectiveness, supplier performance, and risk indicators. 

• ERP & Systems Strategy: Own the strategic roadmap for ERP (NetSuite) and related systems to enhance data visibility, forecasting, and decision-making across the supply chain function. 

• Regulatory & Compliance: Ensure all supply chain activities are fully compliant with FDA, ISO, and QMS standards and support ongoing audit readiness and regulatory inspections. 

• Executive Collaboration & Leadership: Serve as a key member of the operations leadership team, providing strategic input and partnership across R&D, Quality, Finance, and Commercial functions. 

• Team Leadership & Development: Build, mentor, and lead a high-performing supply chain organization, fostering a culture of accountability, collaboration, and continuous improvement. 

• Other duties as assigned. 

Who You Will Report To:

• Senior Vice President, Operations

Requirements:

• Education: Bachelor’s degree in Business, Engineering, Supply Chain Management, or equivalent; MBA or advanced degree strongly preferred. 

• Experience: 15+ years of progressive supply chain experience, including 7+ years in senior leadership roles within the medical device or regulated life sciences industry. 

• ERP Expertise: Demonstrated success implementing and optimizing ERP systems; NetSuite experience highly preferred. 

• Technical Skills: Strong proficiency in Microsoft Office (Excel, Word, PowerPoint, Outlook) and supply chain analytics tools. 

• Organizational Skills: Strategic thinker with strong executional discipline and the ability to manage multiple priorities in a fast-paced environment. 

• Communication & Negotiation: Strong executive communication and negotiation skills, with experience managing complex supplier and stakeholder relationships. 

• Supplier Relationship Management: Proven ability to establish and sustain global supplier networks, including performance management and risk mitigation. 

• Teamwork & Leadership: Experienced leader of cross-functional and cross-cultural teams, with a commitment to mentoring and team development. 

• Employee Development and Management: Demonstrated ability to lead, coach, and develop both professional and hourly staff in a growth-focused environment. 

• Problem-Solving & Urgency: Ability to anticipate and resolve complex supply chain challenges with a proactive, data-driven approach. 

• Regulatory Knowledge: Deep knowledge of FDA and ISO regulatory requirements applicable to medical device supply chain operations. 

• Certifications: APICS, Six Sigma, or other supply chain-related certifications are a plus. 

• Work location: Pleasanton, CA 

• Travel: 10% 

• Full-time employment 

• Physical Requirements: Must be able to lift 10 pounds and sit for up to 8 hours/day 

• Compliance: Must comply with relevant county, state, and federal rules regarding vaccinations 

What We Offer: 

At Calyxo, you will be part of a knowledgeable, high-achieving, experienced, and fun team. You will work in a diverse work environment with experienced, proven leaders and have an opportunity to shape our company culture. You will experience constant learning and dynamic challenges to help you grow and be the best version of yourself.

We also offer an attractive compensation package, which includes

• A competitive and generous base salary ranging from $190,000 to $260,000 per year and a variable incentive plan  

• Stock options—ownership and a stake in growing a mission-driven company 

• Employee benefits package that includes 401(k), healthcare insurance, and paid vacation 

Calyxo is deeply committed to fostering an environment where diversity and inclusion are not only valued but also prioritized. We believe a diverse and inclusive community empowers us to act courageously, care deeply, and dream boldly to impact people in big ways. Diverse viewpoints bring diverse capabilities, which strengthen our focus and fuel our growth. 
 
Calyxo is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status or any other applicable legally protected characteristics

Legal authorization to work in the United States is required. In compliance with federal law, all persons hired will be required to verify their identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire. 

Disclaimer:

At Calyxo, we prioritize a transparent and structured interview process to ensure the best fit for both our candidates and our team. Please be aware of the following:

• Structured Interview Process: Our hiring process includes multiple stages of interviews where you will have the opportunity to communicate directly with Calyxo employees. This ensures that you gain a comprehensive understanding of the role and our company culture.
• Verification of Identity: We do not extend job offers without first meeting candidates, either virtually or in person. This step is crucial to maintain the integrity of our hiring process and to ensure mutual alignment.
• Beware of Scams: Calyxo will never request sensitive personal information, such as your full name, address, phone number, or identification documents, via email or online forms before an official interview. Calyxo representatives will always contact you using an email format of firstname.lastname@calyxoinc.com. If you receive a request for information from any other domain, please contact us directly at info@calyxoinc.com to verify the legitimacy of the communication.

We appreciate your interest in joining Calyxo and look forward to getting to know you through our official channels.