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Sr. Lab Operations Manager

Watertown, Massachusetts, United States

The Company

Dyno Therapeutics is reshaping the gene therapy landscape through AI-powered vectors. Through the application of our transformative technologies and strategic partnerships with leaders in gene therapy, we believe a future with life changing gene therapies for millions of people is within reach. 

Our team includes world-class molecular and synthetic biologists, protein engineers and gene therapy scientists working alongside software engineers, data scientists, and machine learning experts to transform the landscape of available gene therapy capsids. Dyno has been named the 2021 NEVY Emerging Company of the Year, an Endpoints 11 Company and one of America’s Best Startups by Forbes in 2022 and 2023!

The Role

Manager/Sr. Manager - Lab Operations. Highly collaborative laboratory operations manager with industry experience who is committed to streamlining laboratory processes in partnership with R&D.  

How You Will Contribute

As Manager/Sr. Manager - Lab Operations you will be responsible for leading effective and efficient laboratory operations, including stewarding laboratory resources, ensuring compliance with safety and regulatory standards, and facilitating a productive research environment to support Dyno’s R&D goals and projects.

Responsibilities: 

  • Effectively steward lab resources, equipment, space, and supplies to support R&D workflows and projects, ensuring R&D goals are met efficiently.
  • Implement strategies to optimize lab operations for cost-efficiency and time-efficiency with an aim to reduce scientists' time spent on operational tasks while maintaining high-quality output.
  • Develop and implement a robust system to ensure shared spaces and equipment are well maintained and functional, minimizing downtime and interruptions to research activities. Document new/updated products and processes as necessary.
  • Nurture the lab community through proactive development, communication, and training of lab personnel, enhancing their research capabilities, skills, and collaboration, to ensure the lab community is maximally successful towards Dyno’s mission. 

Who you are

  • Trusted partner
  • Highly collaborative
  • Team oriented
  • Thoughtful & detail oriented 
  • Work with a sense of urgency
  • Appreciation for opportunities at the intersections of data science and biology

Basic qualifications

  • BS degree with 3-5 years of proven expertise in managing lab resources, equipment, and supplies within a biotech or pharma environment.
    • Experience with cradle-to-grave equipment management (including installations, service contracts, preventative maintenance, corrective repairs, etc.) and Point of Use inventory management. 
  • Strong ability to develop and implement strategies for optimizing lab operations, with a focus on cost-efficiency, time-efficiency, and maintaining compliance with regulatory protocols. 
  • Proficiency in developing and managing robust systems for the maintenance of shared spaces and equipment to minimize downtime and interruptions to R&D activities.
    • Proven experience leading lab space planning and retrofits.
  • High-level understanding of mechanical, electrical, and plumbing (MEP) utilities as they pertain to research labs.
  • Exceptional leadership skills with the capacity to foster the development, communication, and training of lab personnel, enhancing their capabilities, skills, and collaboration for maximum R&D success.
  • Excellent problem-solving skills to address operational challenges, flexibility to adapt to changing R&D needs, and continuously improve lab processes to achieve the desired outcomes.
  • Track record of successfully interfacing with external service providers and contractors, as well as collaborating with internal support teams.

Preferred qualifications

  • Experience with sourcing and/or vendor-managed inventory (VMI) systems.
  • DOT 49 CFR Hazardous Materials Regulations (HMR) trained with domestic and international shipping experience.
  • Previous experience managing direct reports.

The Culture

At Dyno Therapeutics, we are a high-energy, high-impact team on a mission to build high-performance genetic technologies that transform patient lives. Our team unites world-class molecular biologists, protein engineers, software developers, data scientists, and machine learning experts—all working together at the intersection of AI and genetic medicine.

Our culture is defined by three core values that guide everything we do:

  • One Mission: Everything we do is for the mission. We are a cohesive and motivated team, thinking ahead and supporting one another to overcome challenges.
  • Proactive Responsibility: We take action, inject energy into our work, and hold ourselves accountable for delivering results.
  • Reaching for Excellence: We constantly strive for excellence, fueled by curiosity, adaptability, and the courage to speak hard truths in pursuit of success.

These values are more than words—they drive our actions and decisions. Our greatest strength isn’t technology—it’s our work ethic. More than just technologists, we’re a team of relentlessly resourceful problem-solvers: with an unshakable drive we generate breakthroughs at the intersection of AI and genetic medicine.

 What You’ll Give:

  • Bring an unstoppable work ethic, stepping up when things get tough and adapting as priorities shift.
  • Embrace challenges as opportunities, finding solutions where none exist and driving innovation forward.
  • Operate with urgency, responsibility, and resilience, because this mission demands the best from us.

 What You’ll Get:

  • Competitive compensation & equity—your contributions drive results, and we pay accordingly.
  • Mission-aligned, high-trust environment—we succeed together, supporting each other through challenges.
  • A career-defining experience—work at the forefront of AI-driven genetic medicine, tackling problems that reshape healthcare.

If you’re ready to push boundaries, build the future, and thrive in a fast-moving, high-impact environment—we’d love to hear from you.

At Dyno, we believe in transparent and equitable compensation practices.

Expected Base Salary Range: 

Manager: $116,793.04 - $139,684.48/year

Sr. Manager: $139,534.78 - $166,883.60

This reflects the typical offer range for this role, based on experience, role scope, and internal equity. Final compensation decisions are made using a consistent leveling framework and consider the candidate’s experience, interview performance, and expected impact.

This role is eligible for:

  • Annual performance-based target bonus 
  • Stock options
  • Comprehensive medical, dental, and vision coverage
  • 401(k) plan
  • Flexible paid time off and holidays
  • Perks including on-campus gym membership, onsite lunch, commuter support, and company provided laptop

Our compensation ranges are reviewed annually to ensure alignment with market trends and internal equity.

Equal Employment Opportunity (EEO) Statement

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Fraud Alert: Please be aware of recruitment scams targeting job seekers. Dyno Therapeutics will never make an offer of employment without conducting a formal interview process, nor will we ask for personal information such as financial details over email. Official communication will only come from an @dynotx.com email address. If you are contacted by someone claiming to represent Dyno Therapeutics from any other domain, please report it as spam and report the communication to us at jobs@dynotx.com.

 

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