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Program Manager II- Site Activations

Cambridge, MA or New York City, NY

Iterative Health is a healthcare technology and services company powering the acceleration of clinical research to transform patient outcomes. The Iterative Health Site Network is a premier network of 70+ clinical research sites across US and Europe accelerating the path to market for gastrointestinal (GI) and hepatology novel therapies. Our focus is on driving the success and growth of our partner sites by empowering them with tech-enabled services. By combining deep expertise in clinical trials with cutting-edge AI, we empower research teams and study sponsors to expand and expedite access to novel therapeutics for patients in need.

About the Role

We are seeking a Program Manager II, Site Activations to own and scale the site activation process across the organization. This role is responsible for driving on-time site activations within SLAs, proactively identifying and resolving blockers, and improving activation workflows to increase speed, predictability, and efficiency.

This role requires a strong operator who can manage complex details and dependencies day-to-day, while also stepping back to identify systemic issues, design better processes, and drive continuous improvement. The Program Manager II operates with a high degree of autonomy and is trusted to run site activations with limited oversight.

Key Responsibilities

Program Ownership & Execution

  • Own the end-to-end site activations, managing timelines, dependencies, and risks across multiple concurrent sites and trials
  • Be able to help teams prioritize tasks across multiple activations
  • Ensure activation milestones are met within defined SLAs, escalating risks and delays proactively
  • Maintain clear activation plans, status tracking, and documentation
  • Serve as the primary point of accountability for activation delivery

Cross-Functional Coordination & Escalation

  • Coordinate across cross-functional partners (e.g., clinical operations, regulatory, legal, professional services)
  • Identify, document, and escalate blockers with clear context, impact, and recommended solutions
  • Drive alignment and follow-through across stakeholders with differing priorities
  • Facilitate discussions and decisions to keep activations moving forward

Process Improvement & Scaling

  • Identify bottlenecks and inefficiencies in the activation lifecycle using data and operational insights
  • Lead initiatives to streamline workflows, reduce activation cycle times, and improve SLA adherence
  • Standardize processes, templates, and operating rhythms to support scale, with an eye towards automation
  • Partner with leadership to evolve the activation model as volume and complexity grow

Metrics & Reporting

  • Own activation-related metrics, including time-to-activation, SLA performance, and root causes of delays
  • Define and maintain reporting and dashboards that provide clear visibility to stakeholders
  • Use data to inform prioritization, process improvements, and resourcing decisions

Leadership & Influence

  • Act as a subject matter expert for site activation processes
  • Influence without authority, driving outcomes through clarity, structure, and accountability

Qualifications

Required

  • 5–8 years of experience in program management, operations, or project management
  • Proven track record of managing complex, cross-functional programs with tight timelines
  • Strong execution skills with exceptional attention to detail
  • Ability to zoom out and think systemically about process design and efficiency
  • Proven track record of delivering process improvements at scale
  • Excellent written and verbal communication skills, particularly around escalation and stakeholder management
  • High degree of ownership, judgment, and comfort operating independently
  • Experience in clinical research, site operations, healthcare, or life sciences

Preferred

  • Experience scaling or maturing operational programs in growing organizations
  • Familiarity with activation tools, workflow systems, or project management platforms

New York pay range

$115,000 - $165,000 USD

At Iterative Health, we’re actively working towards creating an environment that is representative of the diversity of patients our technology serves. We are focused on building an equitable and inclusive culture, and by extension, hiring process. If you require any accommodations to make the application process or interviewing experience more accessible to you, please contact CandidateAccommodations@iterative.health.

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