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Associate Director, Head of Contract Management

Cambridge, MA

Company Overview:

Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.  

Prime Medicine is currently progressing a diversified portfolio of eighteen programs initially focused on genetic diseases with a fast, direct path to treating patients or with a high unmet need because they cannot be treated using other gene-editing approaches. Over time, the Company intends to maximize Prime Editing’s therapeutic potential and advance potentially curative therapeutic options to patients for a broad spectrum of diseases. For more information, please visit www.primemedicine.com.

Position Overview:

Prime Medicine is seeking an experienced and detail-oriented Head of Contract Management to lead our contract management function. This role is responsible for overseeing the end-to-end lifecycle of commercial contracts, including drafting, negotiation, execution, compliance monitoring, and renewal. The ideal candidate will be a strategic thinker with strong leadership skills, legal and commercial acumen, and a track record of optimizing contract processes to support business goals and manage risk.

Responsibilities:

  • Lead and manage the Contract Management team, ensuring efficient and compliant contract operations across the organization.
  • Develop, implement, and continuously improve contract management policies, procedures, and systems.
  • Oversee the preparation, review, negotiation, and execution of a wide range of commercial contracts (e.g., MSAs, CDAs, consulting agreements, license agreements, material transfer agreements, clinical trial agreements).
  • Collaborate with Legal, Procurement, Finance, Operations, and other stakeholders to align contract strategies with business objectives.
  • Maintain and enhance centralized contract repository and ensure accurate contract tracking and reporting.
  • Mitigate contractual risk by identifying and addressing legal and business issues in agreements.
  • Monitor compliance with contractual obligations, including service level agreements, milestones, and payment terms.
  • Support audits and due diligence processes by providing contract documentation and analysis.
  • Provide training and guidance to internal teams on contract management best practices.
  • Stay informed on relevant legal and regulatory developments affecting contractual obligations and risk.

Qualifications:

  • Bachelor’s degree in Law, Business Administration, or a related field; JD or equivalent legal qualification preferred.
  • Minimum of 5–7 years of experience in contract management, with at least 2 years in a leadership role preferred.
  • Proven experience managing complex agreements in life sciences field.
  • Strong understanding of contract law, negotiation techniques, and risk management.
  • Exceptional leadership, communication, and stakeholder management skills.
  • Proficiency with contract lifecycle management (CLM) systems and tools.
  • Detail-oriented, analytical, and capable of handling multiple priorities in a fast-paced environment.

Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.

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