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Bioinformatics Scientist

Research Triangle Park, NC

(ID: 2026-2422)


Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).


Axle is seeking a Bioinformatics Scientist to join our vibrant team at the National Institutes of Health (NIH) supporting the Research Triangle Park, NC.


Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

Position Information:

 

The position will independently provide support services to satisfy the overall operational objectives of the National Institute on Environmental Health Sciences.

 

Additional Qualifications:

 

Certifications & Licenses

  • Ph.D. in Bioinformatics, Biostatistics, Computational Biology or a biological/life science

 

Field of Study

  • Mathematics and Computer Science

  • Biology

  • Environmental Science

  • Genetics

  • Molecular Biology

 

Software

  • R

  • Python

  • MATLAB

  • Linux

  • PERL

  • Unix

  • Shell

  • Java

 

Skills

  • Next gen sequencing data analysis: Bulk RNA-Sequencing

  • Next gen sequencing data analysis

  • Clinical and/or translational research

  • Single Cell RNA-Sequencing

  • Work with large data sets

  • Microarray data analysis

  • Pipeline development

  • Methylation Analysis

  • Multi-omics Analysis

  • Cluster Analysis

  • Core facility

 

Deliverables:

 

  • Work products and documents related to conducting data analyses on NextGen sequencing data; analyzing and interpreting data from genomic platforms, including expression microarrays and others. - Ad-Hoc

  • Work products and documents related to identifying and discovering analyses of differentially expressed genes; calculating fold change, p-values, multiple test adjustments and custom analyses; conducting data quality analyses/assessments, analyses of raw and normalized data using graphical techniques. - Ad-Hoc

  • Work products and documents related to developing and/or managing workflows,
    experimental design, analyses of data quality, genome and meta-genomic context and
    others. - Ad-Hoc

  • Work products and documents related to writing custom programs and algorithms; designing models summarizing/explaining experimental data; preparing reports and publication quality graphics; participating in meetings. - Ad-Hoc

 

Statement of Work Details:

 

  • Conduct analyses on NextGen sequencing data including data derived in ChIP-Seq, RNA-Seq, miRNA-Seq and other experimental
    models. - 1
  • Conduct analysis and interpretation on data from genomic platforms including expression, exon, tiling, promoter and others array types. - 2
  • Conduct data analysis and interpretation on other large data types in genomic context. - 3
  • Establish and maintain workflows including experimental design, analyses of data quality, genome and meta-genome integration and
    others. - 4
  • Write utility scripts, macros and/or custom programs or algorithms in support of biological discovery. - 5
  • Coordinate with biologists and/or other bioinformaticians in the design of models summarizing and explaining experimental data;
    provide interpretive analyses of data derived from different experimental platforms to generate biological meaning.

  • Prepare reports and publication quality graphics summarizing experimental data including providing written documents

  • Participate in meetings with biologists; present findings to individuals and groups.


Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.


The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.


Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com


This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

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