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Integrative Structural and Computational Virology Scientist

Hybrid/Northeast

ABOUT US

There are more than 9 million immunocompromised people in the United States. Almost half a million of those represent a population that are moderately to severely immunocompromised and at highest risk for severe COVID-19, including stem cell and solid organ transplant patients as well as those with hematologic cancers.

At Invivyd, Inc., we take those numbers very seriously and we come to work each day on a mission to deliver protection from serious viral infectious diseases, beginning with SARS-CoV-2. Our proprietary INVYMAB™ platform approach combines state-of-the-art viral surveillance and predictive modeling with advanced antibody engineering, designed to facilitate the rapid, serial generation of new monoclonal antibodies (mAbs).

Join an incredible team of innovators, disrupters, predictive modelers, and antibody engineers who embrace a shared sense of ownership, a passion to save lives, think boldly and creatively, take targeted risks, are unafraid of failure, and welcome change as a positive catalyst to new opportunities.

Be part of making a difference. Be part of Invivyd.

In this role you will be responsible for executing the Invivyd preclinical development strategy in support of regulatory filings and clinical programs. This position will work collaboratively across research and clinical teams to ensure planning, execution, and delivery of the strategy for preclinical candidates.

Position Summary: 
We are seeking a highly motivated and versatile PhD Scientist to join our team. In this role you will be responsible for executing the Invivyd preclinical development strategy in support of regulatory filings and clinical programs. This position will work collaboratively across research and clinical teams to ensure planning, execution, and delivery of the strategy for preclinical candidates. This role will report directly to the Director of Antibody Discovery and Nonclinical Development and will serve as a key contributor across various projects. The successful candidate will be responsible for designing, executing, and reporting on nonclinical in vitro and in vivo studies aimed at discovering, characterizing, and developing best-in-class antibodies for the prophylaxis and treatment of viral infections. This position offers a unique opportunity to work across multiple functions, including research, clinical/medical, preclinical safety/toxicology, development, and regulatory teams, as well as managing work with CROs and collaborators. 

Key Responsibilities: 

  • Nonclinical Study Leadership: Lead nonclinical studies from discovery through life-cycle management, including the design, execution, interpretation, and reporting of in vitro and in vivo studies.
  • Antibody Discovery & Development: Contribute to the discovery, characterization, and nomination of therapeutic antibodies, bringing innovative scientific knowledge to project teams.
  • Cross-functional Collaboration: Work collaboratively across research, clinical/medical, preclinical safety/toxicology, development, and regulatory teams to advance projects.
  • CRO and Collaborator Management: Identify, select, and oversee CROs and external collaborators to ensure timely initiation, progression, and completion of nonclinical studies.
  • Regulatory Support & Document Authoring: Support regulatory writing, including the drafting of technical reports, patenting strategies, and other documentation necessary for regulatory submissions.
  • Publication & Data Distribution: Own the publication and distribution of research data in alignment with the corporate publication strategy; present findings internally and externally.
  • Project Planning & Management: Assist in project planning, including developing target product profiles and managing timelines and budgets for outsourced studies.
  • Innovation & Technology Exploration: Explore new technologies and methodologies to enhance the discovery and development processes. 

Qualifications: 

  • PhD in a relevant scientific discipline (e.g., Molecular Biology, Biochemistry, Immunology, Virology, Computational Biology).
  • Strong laboratory background with experience in antibody discovery and nonclinical development.
  • Expertise in the technical and scientific aspects of nonclinical efficacy evaluation of antibody therapies, preferably in infectious diseases.
  • Proficiency in computational biology tools and bioinformatics is a plus.
  • Experience in managing CROs and external collaborations, including budgeting and timeline management.
  • Proven track record of scientific contributions, demonstrated by publications, reports, and presentations.
  • Familiarity with regulatory guidelines and nonclinical study design.
  • Strong problem-solving skills and the ability to adapt to evolving project needs.
  • Excellent verbal and written communication skills.

At Invivyd we strive to create a welcoming and inclusive environment. Here all applicants will receive equal consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other applicable legally protected characteristics.

Invivyd is proud to be an equal opportunity employer.

 

 

We do not accept unsolicited resumes from agencies. 

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