Research Associate I, Pharmaceutical Development (Contactor)

Nurix Therapeutics is a biopharmaceutical company focused on the discovery, development and commercialization of small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. Leveraging Nurix’s extensive expertise in E3 ligases together with its proprietary DNA-encoded libraries, Nurix has built DELigase, an integrated discovery platform to identify and advance novel drug candidates targeting E3 ligases, a broad class of enzymes that can modulate proteins within the cell. Nurix’s drug discovery approach is to either harness or inhibit the natural function of E3 ligases within the ubiquitin proteasome system to selectively decrease or increase cellular protein levels. 

Nurix’s wholly owned pipeline comprises targeted protein degraders of Bruton’s tyrosine kinase, a B-cell signaling protein, and inhibitors of Casitas B-lineage lymphoma proto-oncogene-B, an E3 ligase that regulates T cell activation. Nurix is headquartered in San Francisco, California.

Position Description

Nurix is looking for a Research Associate, Pharmaceutical Development to provide scientific, technical, and hands-on support of drug discovery and product development related to small molecules from early discovery to clinical trial enabling studies.

• Prepare and characterize preclinical formulations in support of multiple programs.
• Perform stability and solubility testing using HPLC/UPLC.
• Assist with pre-formulation and formulation development for oral solid dosage forms.
• Contribute to internal and external presentations and publications.

Required Qualifications

• Thorough understanding of basic chemistry principles
• Excellent basic quantitative laboratory skills including weighing, pipetting, and use of volumetric glassware.
• Strong basic HPLC/UPLC skills and understanding (XRD and Mass Spec experience a plus)
• Excellent organizational and documentation skills
• Proficiency in Microsoft 365
• 1-2 years industrial experience preferred
• BS/BA or higher in chemistry, pharmaceutics, or related field

Application Process

Nurix is an Equal Opportunity Employer offering a competitive salary and benefits package. Applicants should be legally entitled to work for any employer in the US.

Note to Employment Agencies: Please do not forward any agency resumes. Nurix will not be responsible for fees related to unsolicited resumes.

Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix.  By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy (https://www.nurixtx.com/privacy-policy/).