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Senior Manager, Insights & Evidence

Remote - USA

At Real Chemistry, making the world a healthier place isn’t just an aspiration—it’s our everyday reality. Our drive to transform healthcare is informed by our blend of deep scientific expertise, human-centred creativity, and AI-driven insights, fostering a unique environment where innovation thrives and our people are impact-obsessed. As a global agency, we provide a full suite of services across healthcare communications and marketing to our clients, including top players in the pharmaceutical and biotech industries.

Our #LifeatRealChem culture is rooted in our people—we believe we are best together and are committed to excellence for both our clients and colleagues. Whether you're a seasoned professional or just starting your career, if you share our passion for healthcare and connection, we invite you to explore our opportunities.

Discover your purpose. Embrace innovation. Experience #LifeatRealChem.

Role Summary:

Real Chemistry is looking for a Senior Manager, Insights & Evidence to join our growing team! The Senior Manager, Insights & Evidence supports evidence generation and synthesis that informs global value, access, and reimbursement strategy. This role will lead evidence-generation and evidence-synthesis workstreams to support value, access, and reimbursement strategy—translating complex clinical, economic, and real-world data into clear, decision-ready insights and narratives for internal teams and external stakeholders.

This is a hybrid role, based in any of our US offices—including Boston, Chicago, Carmel, Lambertville, or Wilmington—or remotely within the US, depending on team and business needs.

Key Responsibilities:

  • Lead and execute evidence synthesis workstreams, including SLRs (protocol development, screening oversight, data extraction, and synthesis) and targeted literature reviews.

  • Develop Global Value Dossiers (GVDs) and supporting modules (clinical, economic, humanistic, epidemiology/burden, unmet need), ensuring strong evidence traceability and version control.

  • Support development of HTA submissions and payer evidence packages; contribute to JCA-aligned evidence planning and content.

  • Translate evidence into strategic insights for market access and value strategy (e.g., value story, evidence gaps, evidence-generation recommendations).

  • Ensure scientific rigor and editorial quality of deliverables (references, tables/figures, methodological transparency, compliance with client/style requirements).

  • Manage project plans and junior staff/contractors (work allocation, feedback, quality review) to deliver on time and within scope.

  • Stay current on evolving evidence standards and trends impacting access decisions, including:

    • HTA requirements and value frameworks

    • Payer evidence expectations and comparative effectiveness

    • RWE guidance and regulatory considerations

    • Measurement/reporting of quality, performance, and outcomes

Required Qualifications:

  • 6–9+ years of experience in HEOR, RWE, market access, medical writing, epidemiology, or related evidence-focused roles (consulting and/or biopharma experience preferred).

  • Demonstrated hands-on experience with SLRs, GVD development, and HTA submission support; familiarity with JCA requirements and implications for evidence packages.

  • Strong ability to synthesize and communicate complex evidence in clear, well-structured written deliverables (reports, dossiers, slide decks).

  • Solid project management skills: scoping workstreams, managing timelines, coordinating reviewers, and maintaining high quality under deadline.

  • Client-service orientation, sound judgment, high attention to detail, and ability to operate effectively in a fast-paced environment.

  • Proficiency with Microsoft Office (PowerPoint, Excel, Word, Outlook).

  • Bachelor’s degree required; advanced degree (MPH, PhD, PharmD, MD, MS) preferred in a relevant discipline.

Pay Range: $90,000-$100,000
This is the pay range the Company believes it will pay for this position at the time of this posting.  Consistent with applicable law, compensation will be determined based on job-related, non-discriminatory factors including but not limited to work experience, skills, certifications, and geographical location. The Company reserves the right to modify this pay range at any time. 

Real Chemistry is proud to be Great Place to Work® certified; check out what our people shared about our culture and workplace on our Great Places to Work Profile here.

We believe we can do our best when feeling our best, which is why we’ve put together a benefits program designed to give you the support you and your family need at every stage of life. Real Chemistry offers a comprehensive benefit program and perks, tailored to your region. Globally, this includes offices in our key markets with free snacks to keep you running all day long, generous holiday and paid time off, options for private medical, dental, and vison plans, and support in saving for the future. Other perks include mental wellness coaching and support and access to more than 13,000 online classes with LinkedIn Learning.  Learn more about our great benefits and perks and search specific offerings in your region at: www.realchemistrybenefits.com.

Working with Real HART: Since the pandemic, we have adapted to how our people told us they want to work. We have office locations in cities in the US, UK, and Europe with many employees and clients that serve as hubs where and when they need us. For employees who are within an hour of one of our offices, we expect attendance in the office two days per week, either at a Real Chemistry office or onsite with clients. We are also actively opening new office locations, so if one opens near you, our Real HART policy will apply. We are not looking for attendance for the sake of attendance but believe that the opportunity to coordinate in-office team meetings, 1:1 meetings with managers, taking advantage of on-site learning, and connecting with client partners is a critical to delivering on our purpose of making healthcare what it should be. Outside of these offices, we have regions, where people work remotely but come together quarterly for collaboration, culture and learning opportunities. We call this our Real Hybrid and Regional Teams (Real HART) approach. Real Chemistry believes we are best together – and our workplace strategy fosters connection and collaboration in person – but also supports flexibility for our people.

Real Chemistry is an Equal Opportunity employer. We continually strive to build and sustain an inclusive and equitable work environment where our employees feel empowered to leverage all they bring from their personal lived experience and professional expertise, to make our team the best in the industry. We encourage motivated and qualified applicants to apply without regard to race, color, religion, sex (including pregnancy), sexual orientation, gender identity/expression, ethnic or national origin, age, physical or mental disability, genetic information, marital information, or any other characteristic protected by federal, state, or local employment discrimination laws where Real Chemistry operates. Should you require accommodations throughout the interview process please let your recruiter know.

*Notice: Real Chemistry and its affiliates' names are being misused by scammers through messaging services, fake websites, and apps. Do not share personal or financial information or make payments to any unverified sources claiming to be connected to Real Chemistry. We are working to stop these unauthorized activities and protect our community. Read more here.

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