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Scientist, MS&T

Somerset, New Jersey, United States

Company Information

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell and natural killer (NK) cell-based immunotherapy. 

Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel) in 2017. Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.

Legend Biotech is seeking a Scientist as part of the Global MSAT team based in Somerset, NJ.

Role Overview

We are seeking a talented Scientist to join our MS&T team, supporting the development, implementation, and optimization of automated manufacturing processes for cellular therapy products, including CAR-T. Working under the guidance of a Senior Scientist/Principal Scientist, you will assist in designing and executing process development experiments, authoring technical documents, and collaborating with cross-functional teams to ensure successful technology transfers to GMP manufacturing groups.

Key Responsibilities  

  • Assist in designing and executing process development experiments
  • Author and review technical documents, protocols, and reports
  • Analyze and present data in a clear and concise manner
  • Ensure GMP compliance in laboratory notebooks, protocols, and reports
  • Collaborate with internal and external partners to evaluate and implement new process technologies
  • Support technology transfer activities to ensure successful implementation of new processes or technologies in GMP manufacturing environments
  • Assist in implementing automation technologies to enhance process efficiency and productivity
  • Collaborate with cross-functional teams to ensure successful implementation of GMP practices and procedures
  • Perform and interpret analytical assays such as flow cytometry, qPCR, ELISA, and other assays to support process development and optimization

Requirements

  • Bachelor's or master's degree in Biochemistry, Biotechnology, Chemical Engineering, or a related field
  • 2-5 years of experience in MS&T, process development, or a related field
  • Strong understanding of cell therapy, automation, and bioprocessing principles
  • Excellent communication and project management skills
  • Ability to work effectively in a fast-paced, dynamic environment
  • Knowledge of automation technologies and GMP practices is a plus
  • Experience in analytical assays such as flow cytometry, qPCR, ELISA, and other assays is highly desired
  • Experience with CAR-T cell therapy or similar cellular therapy products
  • Familiarity with design of experiments (DOE) and statistical process control (SPC)
  • Experience with data analytics and visualization tools

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Legend Biotech is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend’s policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

Legend Biotech maintains a drug-free workplace.

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