Director, Formulation Development

Mavericks Wanted

When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on
 
In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible. 
 
Together we define white space, push boundaries and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma.

Affiliate Overview

QED Therapeutics, an affiliate within BridgeBio Pharma, focuses on developing targeted treatments for FGFR-driven skeletal dysplasias, particularly Achondroplasia. Achondroplasia is the most common form of genetically driven short stature, which causes potentially debilitating medical complications. With our experimental therapeutic candidate, infigratinib, we seek to provide an option to children living with Achondroplasia and their families.

What You'll Do

The Director, Formulation Development, will join a lean team that enables the commercial and clinical supplies of Infigratinib. This individual will ensure the support of an efficient, uninterrupted supply of medicine by developing strategies to improve our CMC/Supply Chain function, play an operational role in the implementation of new methods, and serve as a key interface between the CMC/Supply Chain team and partners across the business (e.g., Commercial, FP&A, Accounting, Legal, BD, Management).

Responsibilities

Develop novel pediatric formulations for Infigratinib

• Partner with the CMC team to transition formulations into full development
• Drug Development and cross-functional leadership to ensure that the

developed formulation meets the requirements for clinical and commercial success

• Work and manage external formulation technology companies to develop novel formulations
• Ensure formulations are stable and have scalable, robust processes
• Minimize the biopharmaceutical differences between the new and commercial formulations to avoid bioequivalence studies
• Manage other scientists (formulation and analytical)
• Create and manage budgets to achieve project success

Where You'll Work

This is a U.S.-based remote role that will require quarterly, or as needed, visits to our San Francisco Office. 

Who You Are

• Passion for getting lifesaving medicines into the hands of patients quickly, efficiently, and compliantly 
• Master’s degree in chemistry/chemical engineering/pharmaceutics, or PhD preferred but not required 
• Experience working with formulation technologies and suppliers
• Excellent project management skills and ability to handle multiple projects simultaneously 
• Ability to work independently and as part of a team 
• Must be comfortable with ambiguity 
• Proactive problem solver
• Fast (extremely fast) learner 
• Strong communication skills 
• Strong leadership skills and ability to influence functional stakeholders to set direction, align work efforts, and ensure outstanding execution
• The ability to travel (up to 20% of the time) is required

Rewarding Those Who Make the Mission Possible

We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return. 

Financial Benefits:

• Market leading compensation 
• 401K with 100% employer match on first 3% & 50% on the next 2%
• Employee stock purchase program
• Pre-tax commuter benefits
• Referral program with $2,500 award for hired referrals

Health & Wellbeing:

• Comprehensive health care with 100% premiums covered - no cost to you and dependents
• Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)
• Hybrid work model - employees have the autonomy in where and how they do their work 
• Unlimited flexible paid time off - take the time that you need
• Paid parental leave - 4 months for birthing parents & 2 months for non-birthing parents
• Flex spending accounts & company-provided group term life & disability 
• Subsidized lunch via Forkable on days worked from our office

Skill Development & Career Paths:

• People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility
• We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching
• We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities