New

Director of Product Management, Oncology (Europe)

Europe; Germany

Please note: We are only considering applicants who reside in France or Germany for this position.

About the Role

We’re seeking a strategic and execution-focused Director of Product Management to lead the development and commercialization of Signatera in Europe and the UK. This role is central to bringing our molecular residual disease (MRD) technology to more patients across Europe. You’ll drive cross-functional collaboration to localize and scale Signatera’s offerings, manage the full product lifecycle, and ensure alignment with European regulatory frameworks such as IVDR.

This is a high-impact role that blends long-term roadmap planning with day-to-day execution. You’ll serve as the bridge between customer needs, business strategy, and technical capabilities—ensuring Signatera’s success in diverse European markets.

Key Responsibilities

  • Lead the European product strategy and execution for the Signatera MRD product line, including commercialization and technology transfers of exome CDx and future genome designs.

  • Drive local IVDR submission strategy and coordinate implementations across countries.

  • Own the product lifecycle from concept through obsolescence, including roadmap development, feature prioritization, and performance evaluation.

  • Define and document product requirements specific to the European landscape, balancing clinical utility, operational feasibility, and regulatory expectations.

  • Work cross-functionally with teams in Europe and the U.S., including R&D, Engineering, Medical Affairs, Regulatory, Quality, Marketing, Sales, and Operations.

  • Monitor and optimize product performance using data-driven KPIs and customer feedback loops.

  • Conduct market research, VOC interviews, and competitive analysis tailored to European markets to validate new opportunities and refine feature sets.

  • Develop business cases and financial models to support prioritization of investments.

  • Support regional go-to-market planning, including pricing strategy, positioning, and marketing collateral.

  • Regularly communicate roadmap progress, vision, and product performance to internal and external stakeholders.

Qualifications

  • Bachelor’s degree required; advanced degree (Master’s, PhD) in life sciences or related field preferred.

  • Minimum of 8 years of experience, including at least 7 in product management, product marketing, commercialization, or strategic consulting.

  • Strong background in oncology, molecular diagnostics, CDx, or IVDR/CE-IVDD-regulated environments.

  • Hands-on experience with high-throughput molecular testing and tumor tissue sequencing is preferred.

  • Demonstrated success transferring diagnostic technologies from the U.S. to Europe or UK markets is highly desirable.

  • Familiarity with life sciences industry best practices and regulatory standards.

Skills & Competencies

  • Ability to lead and motivate cross-functional, multinational teams.

  • Strong technical acumen with the ability to translate complex science into customer-focused solutions.

  • Proficient in project management and capable of handling multiple concurrent initiatives.

  • Excellent communication skills—both written and verbal; fluent in English is required.

  • Proficiency in German, French, or another European language is a strong plus.

  • Proficient in standard business software, including Excel, PowerPoint, and project management tools.

  • Analytical thinking and basic financial modeling skills for business case development.

  • Comfortable interacting with senior leadership and influencing across functions.

Work Environment & Requirements

  • Primarily office-based or remote with standard computer and phone use.

  • Must be able to collaborate with teams across U.S. time zones (Central and Pacific).

  • Occasional travel may be required.

  • Flexibility to work outside normal business hours when collaborating with global teams.

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents. 

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
- BBB announcement on job scams 
- FBI Cyber Crime resource page 

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