Manager, EH&S
Company Overview:
Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.
Prime Medicine is currently progressing a diversified portfolio of eighteen programs initially focused on genetic diseases with a fast, direct path to treating patients or with a high unmet need because they cannot be treated using other gene-editing approaches. Over time, the Company intends to maximize Prime Editing’s therapeutic potential and advance potentially curative therapeutic options to patients for a broad spectrum of diseases. For more information, please visit www.primemedicine.com.
Position Overview:
As the Manager, EH&S, you will be responsible for developing, implementing, and maintaining environmental health and safety programs to ensure compliance with federal, state, and local regulations, as well as company policies. You will work closely with lab managers, scientists, and other departments to foster a culture of safety and mitigate risks associated with biological, chemical, and animal research activities.
Key Responsibilities:
- Create overall company safety plan.
- Develop, implement, and maintain EH&S policies, procedures, and training programs for biology, animal, and chemistry laboratories.
- Monitor and enforce adherence to safety regulations and best practices.
- Conduct regular safety audits, inspections, and assessments of laboratory and facility areas to identify potential hazards and recommend corrective actions.
- Analyze and assess risks associated with new or modified laboratory processes and materials.
- Ensure compliance with OSHA, EPA, FDA, NIH, and other relevant regulations governing biotech labs, including those dealing with hazardous chemicals, biological agents, and animal handling.
- Prepare and submit required reports to regulatory agencies, ensuring all licenses and permits are up to date.
- Develop and conduct training for lab personnel on topics such as chemical safety, biological safety, personal protective equipment (PPE) usage, waste management, and emergency response protocols.
- Maintain accurate records of all safety training activities and certifications.
- Investigate safety incidents, near-misses, and accidents to identify root causes, ensure corrective actions are taken, and minimize recurrence
- Coordinate emergency response drills (e.g., fire drills, chemical spill response) and manage the lab's emergency response procedures.
- Oversee the safe disposal of hazardous materials, biohazardous waste, and chemical waste in accordance with local, state, and federal laws.
- Promote sustainable practices and initiatives to minimize environmental impact.
- Work closely with R&D, Facilities, and Operations teams to support safety in lab design, equipment procurement, and operational workflows.
- Provide guidance and support to project managers and scientists on EH&S matters as they arise.
Qualifications:
Education:
- Bachelor’s degree in Environmental Health & Safety, Biology, Chemistry, or related field. A Master’s degree or relevant certification (e.g., CIH, CSP) is a plus.
Experience:
- 5+ years of experience in EH&S or Laboratory Operations, with at least 2 years in a biotech, pharmaceutical, or life sciences environment.
- Experience working in biology, chemistry, or animal research labs is strongly preferred.
- Knowledge of relevant EH&S regulations, including OSHA, EPA, FDA, and NIH guidelines.
Skills:
- Strong knowledge of laboratory safety protocols and risk management.
- Ability to assess and mitigate hazards in a laboratory setting (biological, chemical, and animal-related).
- Strong interpersonal and communication skills with the ability to effectively train, advise, and collaborate with teams across multiple disciplines.
- Excellent organizational and problem-solving skills, with attention to detail.
- Ability to prioritize and manage multiple tasks simultaneously in a dynamic environment.
Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.
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