Back to jobs
New

Global Director Platform Innovation

Raritan, New Jersey, United States

Legend Biotech is seeking a Global Director of Platform Innovation as part of the Technical Operations team based in Raritan, NJ. 

Role Overview

Legend Biotech is seeking a Global Director of Platform Innovation within our Global MSAT organization to drive the next generation of manufacturing advancements and commercial process platform for our Cell Therapy programs. Based in Somerset, NJ, this critical leadership role will focus on identifying, developing, and implementing innovative process technologies and solutions that enhance manufacturing robustness, scalability, and cost-efficiency resulting in improved commercial manufacturing processes and outcomes.


The Director will build and lead a high-performing small team of technical experts, fostering a culture of scientific curiosity, execution excellence, continuous improvement and data driven decision making. The role requires strong collaboration across Site MSAT teams, Manufacturing, Quality, Process Development, and Engineering to ensure that innovative solutions are successfully transferred into GMP manufacturing sites.

This position is also a critical contributor to the technical leadership function in the global MSAT organization. Additionally, this individual is required to drive the success and overall sustainability of global commercial process platform by adhering to industry best practices and sound cell therapy technical principles. Strong collaboration and partnering is required to implement process improvements, optimization, capacity expansion, and cost of goods / non-conformance reduction efforts worldwide.

Key Responsibilities  

  • Lead innovation programs focused on enhancing cell therapy manufacturing processes through advanced processing, automation, digital technologies, and platform optimization.
  • Build, manage, and mentor a small, agile team of engineers and scientists dedicated to process innovation initiatives.
  • Seek out, propose, evaluate, and implement novel technologies to improve yield, consistency, scalability, and reduce cost of goods (COGS) across autologous and allogeneic platforms.
  • Design and oversee proof-of-concept studies, process characterization efforts, and critical parameter definition for late-stage and commercial manufacturing.
  • Develop technology and process platform roadmaps
  • Develop key event milestones as part of project planning / oversight in support of tech transfer activities
  • Drive cross-functional collaboration with Site MSAT, Manufacturing Operations, Quality, Process Development, and Regulatory to facilitate seamless implementation of process changes and solutions.
  • Present proposals and projects to various technical forums like CMC
  • Develop strong business cases for new technology adoption, articulating operational, financial, and compliance benefits to leadership.
  • Lead or support process validation, regulatory submissions, and regulatory inspection readiness related to innovation and continuous improvement initiatives.
  • Work collaboratively with internal and external partners to drive global process platform improvements and cost reduction initiatives
  • Serve as a technical leader and subject matter expert during regulatory engagements (FDA, EMA) on manufacturing innovation topics.
  • Foster a culture of innovation, data-driven decision-making, and proactive problem-solving across Global MSAT.
  • Stay informed on industry trends, emerging technologies, and competitive landscape in cell and gene therapy manufacturing.

Requirements

  • B.S. required, Ph.D. preferred in technical discipline: engineering, science, or related field.
  • 12+ years of experience in biopharmaceutical process development, MSAT, or manufacturing, with a strong focus on cell and gene therapy.
  • Demonstrated success in leading process improvement and technology integration initiatives within process development or GMP environments.
  • Experience building and managing technical teams in matrixed, cross-functional environments.
  • Expertise in scaling cell therapy technologies, process validation, and regulatory filings (IND, BLA).
  • Candidate must have extensive experience in Cell Therapy process development, tech transfer and/or MSAT.
  • Strong leadership and people development skills.
  • Ability to influence and collaborate effectively across multiple departments and global sites.
  • Strategic and operational thinker with excellent execution capability.
  • Outstanding interpersonal, communication, and stakeholder management skills.
  • Direct experience with CAR-T therapy manufacturing and/or autologous workflows.
  • Strong background in cell processing automation (e.g., Prodigy, Rotea, CliniMACS) and closed-system technologies.
  • Experience leading technology transfers and implementing process changes and/or new process versions in a regulated environment across a global manufacturing network.
  • Familiarity with digital manufacturing systems (e.g., MES, SCADA) and data analytics platforms.

#Li-JK2

#Li-Hybrid

The anticipated base pay range for this is: $163,468 - $224,769 USD. 

Legend Biotech is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend’s policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

Legend Biotech maintains a drug-free workplace.

Apply for this job

*

indicates a required field

Resume/CV*

Accepted file types: pdf, doc, docx, txt, rtf

Cover Letter

Accepted file types: pdf, doc, docx, txt, rtf

Select...
Select...
Select...
Select...
Select...
Select...
Select...
Select...

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Legend Biotech US’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Select...
Select...
Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Select...

Voluntary Self-Identification of Disability

Form CC-305
Page 1 of 1
OMB Control Number 1250-0005
Expires 04/30/2026

Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
  • Traumatic brain injury
Select...

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.